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Biofluid Testing

Hematology analysis, bio fluid chemistry, and biomarker services

Our non-GLP biofluid tests provide robust, high-quality data for early-stage preclinical drug development. These services provide a rapid, cost-effective way to analyze blood and urine samples as a standalone service, or supplementary to in vivo studies.

Analytes listed in the following sections are subject to change. Please contact your local business development specialist for our current offerings. Additional assays are available with a validation lead time of approximately 2-3 weeks.

Blood and Urine Chemistry Analysis

Gain valuable information about drug efficacy, candidate selection, MoA, and enzymatic activity using a comprehensive portfolio of clinical chemistry assays developed on the Beckman Coulter® AU480 Chemistry Analyzer and Sysmex BX-3010 Automatic Chemistry Analyzer.

Blood and Urine Chemistry Analysis Sample Panel

Alanine aminotransferase (ALT) Hemoglobin A1C (HBA1c)
Aspartate aminotransferase (AST) Homocysteine
Albumin (ALB) Ion-specific electrode (ISE: Na, K, CL)
Alkaline Phosphatase (ALP) Iron
Beta-2-Microglobulin (B2M) Lactate dehydrogenase (LDH)
Bicarbonate (CO2) LDL Cholesterol
Calcium Lipemia, Icterus, Hemolysis (LIH)
Cholesterol Lipase
C-Reactive Protein (CRP) Magnesium
Creatine Kinase Urine Total Protein (MTP)
Creatinine Phosphorus
CYSC Total Bilirubin
Direct Bilirubin Triglyceride
GGT (Gamma-Glutamyltransferase) Urea Nitrogen (BUN)
Glucose Uric Acid
HDL Cholesterol Urine Albumin

Complete Blood Count (CBC)


  • Element HT5 Veterinary Hematology Analyzer
  • VETSCAN ® HM5 Hematology Analyzer

Complete Blood Count Sample Panel

White Blood Cell Count (WBC)
Lymphocytes (LYM)
Monocytes (MON)
Neutrophils (NEU)
Percentage of White Blood Cells (WBC%)
Percentage of Lymphocytes (LYM%)
Percentage of Monocytes (MON%)
Percentage of Neutrophils (NEU%)
Red Blood Cell Count (RBC)
Hematocrit (HCT)
Mean Corpuscular Volume (MCV)
Red Cell Distribution Width (coefficient of variation) (RDWc)
Red Cell Distribution Width (standard deviation) (RDWs)
Hemoglobin (HGB)
Mean Corpuscular Hemoglobin (MCH)
Mean Corpuscular Hemoglobin Concentration (MCHC)
Platelet Count (PLT)
Mean Platelet Volume (MPV)
Platelet Crit (PCT)
Platelet Distribution Width (coefficient of variation) (PDWc)
Platelet Distribution Width (standard deviation) (PDWs)

Biomarker Analysis Services

Translational biomarkers are used throughout drug development to help elucidate underlying pathophysiology, understand an agents’ mechanism of action, measure efficacy, and stratify patient populations. We provide a panel of routinely performed immunoassay services to inform decision-making in drug development, as well as developing, validating, and performing custom assays.

Meso Scale Discovery® (MSD) Biomarker Assays

Run your samples on MSD’s electrochemiluminescence technology platform. Using the Sector S 600, biomarkers can be customized into a V-PLEX or U-PLEX plate with up to 10 biomarkers of your choice.

MSD Assay Sample Panel

Rodent Assays Human and Nonhuman Primate Assays
(NHP Valided Kits)
Mouse Adiponectin 4-Spot Prototype Human Insulin, C-Peptide for NHP
Mouse IL-1b Human/NHP Glucagon
Mouse IL-2 Human/NHP Adiponectin
Mouse IL-4 Human/NHP Total GIP
Mouse IL-5 Human/NHP Insulin
Mouse IL-6 NHP Total GLP-1 (ver. 2 Kit)
Mouse IL-10  
Mouse Leptin  
Mouse MIP-3a  
Mouse Pro-inflammatory 7plex, tissue culture  
Mouse Pro-inflammatory Panel 1
(IFN-ץ, IL-1β, IL-2, IL-4, IL-5, IL-6, KC/GRO, IL-10, IL-12p70 and TNF-α)
Mouse TGFB1  
Mouse TNF-a  
Mouse/Rat GLP-1 (7-36 amide)  
Mouse/Rat Glucagon  
Mouse/Rat Insulin  
Mouse/Rat Insulin/Glucagon  
Mouse/Rat Total Active GLP1, Insulin, Glucagon  
Mouse/Rat Total GLP-1  
Rat BNP  
Rat IL-1a  
Rat IL-1b  
Rat IL-4  
Rat IL-5  
Rat IL-6  
Rat IL-13  
Rat Kidney Injury Panel 1
(Urine Albumin, KIM-1, NGAL/LCN2, Osteopontin)
Rat MCP-1  
Rat Pro-inflammatory Panel 2
(IFN-γ, IL-10, IL-13, IL-1β, IL-4, IL-5, IL-6, KC/GRO, TNF-α)
Rat TNF-a  

Colorimetric ELISA Biomarker Assays

Evaluate biomarkers on our standard, colorimetric, enzyme-based ELISA platform.

ELISA Assay Sample Panel

Rodent Assays Human and NHP Assays
Mouse Hydroxyproline Human Cortisol
Mouse Urine Albumin Human IGFBP-1
Mouse/Rat Corticosterone Human STELLUX Chemi Insulin
Mouse/Rat/Human Free Glycerol  
Rat Alpha-Fetoprotein  
Rat Fecal Corticosterone Cayman  
Rat Growth Hormone  
Rat TGFB1  
Rat Urine Albumin  
Rodent STELLUX Chemi Insulin  

Service Details

Turn Around Time: 5-7 business days (clinical chemistry), 7-10 business days (MSD & ELISA) Data Delivery Format: Excel File, unless otherwise requested

Assay Validation

To ensure you receive reliable data, we perform rigorous quality control and assay qualification procedures to ensure precision and accuracy. Our high quality results enable you to make preclinical go/no-go decisions with confidence.

Crown Bioscience's custom-fit, 7-point standard curves used to calculate accurate and precise concentrations for IL-10 and TNF-α.

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