Prostate Cancer Preclinical Models

Translational in vitro, in vivo, and immuno-oncology models to progress your prostate cancer agents

Advance Your Prostate Cancer Drug Development with Translational Preclinical Models

Prostate cancer is a highly heterogeneous and complex disease, with evolving treatment options over the course of disease progression. Preclinical research needs a variety of models to fully capture all phases of the multistage disease, and to evaluate a wide range of different therapies.

We provide well-characterized and fully validated preclinical in vivo and in vitro models to evaluate your prostate cancer therapy, including hormone responsive and castrate-resistant:


For immunotherapy assessment we provide a range of models from basic syngeneics, to murine tumor homografts and humanized models.

Learn more on how our models can help advance your drug discovery with our wide range of prostate cancer resources.

Access CrownBio's Online Databases

Looking for data and characterization around a specific model? Explore CrownBio's unique, online databases for a detailed look into the largest collection of preclinical oncology models available.

Easy access for new and current CrownBio Database users: Begin exploring or register now

  • HuBaseTM: Online, searchable database featuring the world's largest PDX collection
  • MuBase®: Online database of murine and humanized drug target models to advance your immuno-oncology research
  • XenoBase®: Online database of over 1,000 tumor cell lines and 215 cell line derived xenograft models

Prostate Cancer Resources


New Advancements in Preclinical Prostate Cancer PDX Models
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Patient-Derived Xenografts: New Advancements in Preclinical Prostate Cancer Models
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progression of prostate cancer from initiation to metastatic, castration resistant disease, including genetic alterations and cellular processes


Why Are Prostate Cancer Preclinical Models Hard to Develop?
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immunohistochemistry images showing that prostate cancer pdx models retain the structure of original patient tumors


Prostate Cancer Patient-Derived Xenograft (PDX) Models
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Prostate Cancer Patient-Derived Xenograft and Cell Line Model Validation
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Discuss Your Prostate Cancer Project