Review our 16 AACR Poster Topics

We're presenting 16 posters at AACR 2018. Preview our topics now, covering a wide variety of preclinical oncology and immuno-oncology platforms including NGS and transcriptomic PDX analysis, novel murine allograft models, as well as PBMC and humanized drug target models for immunotherapy assessment.

OmniScreenTM Large-Scale Cell Screening Platform

Q1 Enrollment Ends March 23rd

Validate your lead compounds with rapid and cost-effective screening of over 500 cancer cell lines.

WEBINAR: In Vitro and Ex Vivo Assays to Accelerate Immuno-Oncology Drug Discovery

28 March 2:00 PM EST / 29 March 9:00 AM EST

Presented by Dr Toni Jun, this webinar introduces a one stop, integrated in vitro/ex vivo I/O assay plaform designed to effciently progress immunotherapy drug development. Learn how to monitor and assess TIL populations and functions, explore the microbiome's role in immunotherapy, and understand a wide range of functional characteristics across the I/O field including tumor microenvironment regulation.

ON-DEMAND WEBINAR: Interrogating Syngeneic Models in Large Scale, How to Use Immunoprofiling Data to Improve your Studies

Presented by Dr Henry Li, this webinar explores the detailed data analysis behind the industry's first large-scale, staggered, syngeneic screening platform for immunotherapy development. Learn how this platform can improve efficiency and reproducibility while reducing cost, how comprehensive immunophenotyping and profiling data is used to address key study design questions, and how RNAseq and FACS/IHC analysis are used for biomarker discovery.

WHITE PAPER: Immuno-Oncology - 3 Strategies for Applying Humanized Models

Enhance your humanized mouse immuno-oncology studies through a deeper understanding of model immunological features and optimized uses. Learn more about immune system humanization strategies, and how these result in different models with contrasting features and limitations, then explore model applications through cancer pharmacology case studies.

Get Your Free Poster

Learn more about the world's largest patient-derived xenograft (PDX) collection. Download or request a poster today.

Watch Henry Li present EORTC 17 Short Talk

Hear Dr Henry Li, Vice President of Biomarker and Diagnostic Technology present our AACR-NCI-EORTC 2017 selected Short Talk titled 'Transcriptomic analysis of patient-derived xenografts reveals heterogeneity in human and mouse stroma/immune compartments'

ON DEMAND WEBINAR: Clinically Relevant Cell-Based Solutions for Target Identification

Learn how to leverage CrownBio's integrated Oncology Portfolio to advance your Target Identification studies. Watch our webinar presented by Michelle Mack.

NEW WHITE PAPER: The Ultimate Guide to Mouse Clinical Trials

Transform your preclinical oncology drug development, with mouse clinical trials using patient-derived xenograft (PDX) models. Learn how the different types of MCT are executed, which is the best fit for your specific drug discovery program, and how they provide the perfect framework for biomarker discovery.

ON DEMAND WEBINAR: How to Maximize Your Non-GLP Toxicology Studies: A Guide for Optimal Design and Methodology

Presented by Dr. Keefe Chng and Dr Judith Gorski this webinar will help guide you through a study design process that will enable the greatest opportunity to generate robust, high-quality data, that gives maximum confidence to select new drug candidates and regulatory submissions.

NEW WHITE PAPER: Translational Platforms to Model Pre-Diabetes, Diabetes, and Diabetic Complications

This White Paper explores a unique platform of highly translational models recapitulating multiple aspects of disease progression as seen in humans, for preclinical efficacy studies.

Clarity with

Recognize your next clinical candidate when you see it.

Our Translational Platforms enable our clients to identify the right patients for the right treatment. Having models which more accurately mimic human disease and population dynamics are key to successfully translating promising compounds into successful clinical candidates, whether treating Oncology or Diabetes related diseases.

Magnify your

Understand the mechanisms of disease.

Our scientific acumen and experience will give you a deeper understanding of not just the pharmacological profile of your compound, but more importantly, a clear understanding of which compounds to progress into the clinic. Take a look at our publications to get a deeper understanding of the depth of our scientific expertise.

Begin with the
end insight

Connecting science to patients.

We help our clients solve some of today's most pressing problems in oncology, cardiovascular, and metabolic disease by answering some of the most challenging questions about human biology.


Models of Obesity


CrownBio’s preclinical Translational Technology Platforms provide spontaneous & diet-induced obesity (DIO) models, to support the transition of new agents into the clinic.

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Oncology Databases


Our unique databases provide a curated source of well-characterized models available to use for drug discovery including PDX models, cell lines, and syngeneic models.

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Diabetes Models


Models of both Type 1 and Type 2 diabetes, including conventional, as well as unique, highly translatable models for in vivo efficacy studies of antidiabetic agents.

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Latest from our Blog

March 19, 2018

Targeting Myeloid Derived Suppressor Cells in Immuno-Oncology

Immune checkpoint inhibitors (ICIs) have dramatically changed the therapeutic approach to cancer, with antibodies against CTLA-4, PD-1, and PD-L1 demonstrating a durable response in selected patients across multiple tumor types.

Read More

March 19, 2018

Targeting Myeloid Derived Suppressor Cells in Immuno-Oncology

Immune checkpoint inhibitors (ICIs) have dramatically changed the therapeutic approach to...

Read More

March 13, 2018

ICOS: Immunostimulatory or Immunosuppressive Target?

The rise of immunotherapy has brought many new targets to the forefront of oncology drug...

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March 7, 2018

New Technique Opens Novel Approaches to Insulin Resistance

A newly-described technique could open multiple lines of investigation into the pathophysiology...

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March 1, 2018

Using T Cells in Immuno-Oncology

Immuno-oncology drug development challenges researchers to model the interaction between novel...

Read More

February 27, 2018

CAR-T Cell Therapy: Use Earlier for Better Results

CAR-T cell therapies are still in their infancy as clinical oncology treatments, with the first...

Read More

Upcoming Events

March 19 - 21, 2018

5th Immunotherapy of Cancer Conference (iTOC5)

Berlin, Germany

Review our Poster Topic

March 28 - 29, 2018

Webinar: In Vitro and Ex Vivo Assays to Accelerate Immuno-Oncology Drug Discovery

Register Now

April 9 - 11, 2018

11th Diabetes Summit

Boston, MA

Preview our Oral Presentation Topic

April 14 - 18, 2018

AACR Annual Meeting 2018

Chicago, Illinois - Booth #3012

Preview our Poster Topics

April 23 - 25, 2018

2nd Annual NASH Summit 2018

Boston, MA

Preview our Poster Topic

May 24 - 25, 2018

3rd Annual Advances in Immuno-Oncology Congress

London, UK

June 22 - 26, 2018

American Diabetes Association 78th Scientific Sessions

Orlando, FL - Booth #1615

Preview our Poster Topics