1820-P: The Depletion of Peripheral NK Cells and NK T Lymphocytes in a Spontaneously Diabetic Non-Human Primate Model
1881-P: Rhythmic Differences of Blood Glucose Circadian between Normoglycemic and Diabetic Non-Human Primates
Join our webinar to discover the wide range of in vivo immuno-oncology preclinical models available, and what to consider when choosing the correct model for your studies. Learn how current models are being used to progress combination regimens, including dual immunotherapies, and I/O agents plus other treatment modalities.
This White Paper explores a unique platform of highly translational models recapitulating multiple aspects of disease progression as seen in humans, for preclinical efficacy studies.
Join our webinar to discover the development and utility of CrownBio's unique continuum of translational platforms modeling diabetes and metabolic syndrome pathophysiology, progression, and complications. Learn how these platforms are predicting the efficacy and safety of anti-diabetic therapies in humans.
Our Translational Platforms enable our clients to identify the right patients for the right treatment. Having models which more accurately mimic human disease and population dynamics are key to successfully translating promising compounds into successful clinical candidates, whether treating Oncology or Diabetes related diseases.
Our scientific acumen and experience will give you a deeper understanding of not just the pharmacological profile of your compound, but more importantly, a clear understanding of which compounds to progress into the clinic. Take a look at our publications to get a deeper understanding of the depth of our scientific expertise.
We help our clients solve some of today's most pressing problems in oncology, cardiovascular, and metabolic disease by answering some of the most challenging questions about human biology.
June 15, 2017
Krill are small crustaceans found in all the world's oceans, which have been harvested as a human and animal food source for many years, recently for use in dietary supplements. A new collaborative study has demonstrated that a novel long-chain (LC) omega-3 rich phospholipid preparation extracted from krill oil can reduce...
June 15, 2017
Krill are small crustaceans found in all the world's oceans, which have been harvested as a...
June 13, 2017
Patient-derived xenograft (PDX) models enhance predictability in oncology preclinical studies....
June 8, 2017
For the first time in their history, the U.S. Food and Drug Administration has approved a cancer...
June 6, 2017
Recent years have witnessed a change in cholesterol-lowering compounds - from your parents’...
June 1, 2017
There's a critical need for novel treatment options to ameliorate insulin resistance,...
HuTrial™
HuPrime®
Immuno-Oncology