November 21, 2024
Organoids, or “mini organs” in a dish, have recently been developed after many decades of attempting long-term stem cell culture. The isolation and growth of Lgr5+ stem cells in vitro by the Clevers lab, alongside the refinement of culture conditions by Hubrecht Organoid Technology (HUB), resulted in a robust technology stably and reproducibly generating organoids from human and murine tissues.
This White Paper explores modern organoids, which recapitulate organogenesis in vitro and are used to investigate stem cell driven disease. HUB Organoid development is also discussed, alongside the key features of these 3D in vitro models leading to their widespread use today.
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2021-10-26
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