H22 Cell Line: A Comprehensive Overview
The H22 cell line, also known as Hepatoma-22, is a widely used model in cancer research, particularly in the field of hepatocellular carcinoma (HCC). This mouse-derived cell line offers valuable insights into the effects of novel anti-cancer therapeutic regimens.
Key Characteristics of H22 Cell Line
- Cancer Type: Liver Cancer
- Mouse Strain: BALB/c
- Response to Immune Checkpoint Inhibitors: (provide response info here)
- Available Models: Subcutaneous and Orthotopic
Special Features of H22 Cell Line at CrownBioscience
At CrownBioscience, we offer the H22 model with unique capabilities. A firefly luciferase-tagged reporter line of the H22 model is available, facilitating disease monitoring via bioluminescent imaging. This allows for precise tracking and monitoring, enhancing the quality of research output.
FAQs about H22 Cell Line
What is the main use of the H22 cell line in research?
The H22 cell line, derived from mouse hepatocellular carcinoma (HCC), is primarily used in cancer research, specifically liver cancer studies. The model enables researchers to evaluate the efficacy and pharmacodynamics changes following novel anti-cancer therapeutic regimens. It's particularly useful in studying the effects of treatments, developing new therapeutic strategies, and understanding the biological and molecular mechanisms of liver cancer progression. Additionally, at CrownBioscience, the H22 model, available as both subcutaneous and orthotopic models, is leveraged for disease monitoring via bioluminescent imaging, offering a valuable tool in tracking tumor growth and response to treatments.