Make Decisions with Confidence in Early Preclinical Cardiovascular and Metabolic Disease Research

Our clinical chemistry and biomarker services provide robust, high quality data for the early preclinical development of your cardiovascular and metabolic disease drugs and diagnostics. These services provide a rapid, cost effective way to analyze samples as a standalone service, or as a supplement to in vivo studies. A range of models and therapeutic areas are covered, with a particular focus on cardio-metabolic endpoints in rodents and non-human primates.

Non-GLP Clinical Chemistry and Biomarker Services

Analytes listed in the following sections are subject to change. Please contact your local business development specialist for our current offerings. Additional assays are available with a validation lead time of approximately 2-3 weeks.

Clinical Chemistry Services

Gain valuable information about drug efficacy, candidate selection, and enzymatic activity using a comprehensive portfolio of clinical chemistry assays developed on the Beckman-Coulter AU480 Chemical System.

Biomarker Services

Translational biomarkers are used throughout drug development to help elucidate underlying pathophysiology, understand agents’ mechanisms of action, measure efficacy, and stratify patient populations. We provide a panel of routinely performed immunoassay services to inform decision making in cardiovascular and metabolic disease drug development, as well as developing, validating, and performing custom assays.

MesoScale Discovery Biomarker Assays

Run your samples on MSD’s electrochemiluminescent technology platform. Using the Sector S600, biomarkers can be customized into a V-PLEX or U-PLEX plate with up to 10 biomarkers of your choice.

Colorimetric ELISA Biomarker Assays

Evaluate biomarkers on our standard, colorimetric, enzyme based ELISA platform.

Service Details

Turn Around Time: 5 to 7 business days (clinical chemistry), 7-10 business days (MSD & ELISA)
Data Delivery Format: Excel File, unless otherwise requested

Assay Validation

To ensure you receive reliable data, we perform rigorous quality control and assay qualification procedures to ensure precision and accuracy. Our high quality results enable you to make preclinical go/no-go decisions with confidence.

CrownBio’s custom-fit, 7-point standard curves used to calculate accurate and precise concentrations for IL-10 and TNF-α.

×

CrownBio’s custom-fit, 7-point standard curves used to calculate accurate and precise concentrations for IL-10 and TNF-α.