Patient-Derived Xenograft (PDX) Models

Over 2,500 clinically-relevant PDX models that truly mimic human disease.

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Leverage the World’s Largest Collection of Highly-Characterized PDX Models

Patient-derived xenografts (PDX) offer the most translational preclinical model for efficacy screening in cancer drug development. Derived directly from patient tumors and never adapted to grow in vitro, PDX models reflect the heterogeneity and diversity of the human patient population.

PDX give you an accurate, predictive model of how your treatment will perform, well before entering into expensive clinical trials.

CrownBio's HuPrime® PDX collection, with over 2,500 well-characterized PDX models, supports translational preclinical oncology research into over thirty human cancer types – including rare indications and highly-specific molecular targets.

ALL
AML
Adrenal
Bladder
Brain
Breast
Cervical
Cholangiocarcinoma
Colorectal
Esophageal
Fallopian
Gallbladder
Gastric
GIST
Head and neck
Kidney
Liver
Lung
Lymphoma
Melanoma
Mesothelioma
Mixed mullerian
Ovarian
Pancreatic
Peritoneal
Prostate
Sarcoma
Testis
Thyroid
Uterine


The CrownBio PDX Collection: 

The HuKemia® Blood Cancer PDX Collection: 

Mouse Clinical Trials with HuTrial™ 

Access the HuBase Database