OmniScreen™ Cell Based Screening Service

Access our regular in vitro screening program for rapid and cost effective screening of over 500 cell lines

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Pinpoint Your Opportunities for Therapeutic Intervention

To provide rapid information on the cytotoxicity and chemotherapeutic potential of your agent early in the drug development process, we have developed a cost effective approach to rapid screening, taking your lead compound to validated candidate.

 

OmniScreen, CrownBio’s Well Validated, Large-Scale Cell Panel Screening Platform

Regular, Cost-Effective Screening

OmniScreen is CrownBio’s global program for large-scale screening of client compounds against our proprietary collections of cancer cell lines, allowing you to:

  • Utilize multiple screening platforms including IncuCyte® ZOOM (real time) and Acumen eX3 (multiparameter)
  • Schedule any subpanel of 50 or more cell lines, with a screening run every 3 months
  • Select from quality cells STR verified and mycoplasma-proofed
  • Choose the models that best fit your needs with XenoBase® our curated, online database of cancer cell lines
  • Customize your study thanks to our flexible template designs
  • Quality control your data against standard of care agents
  • Obtain bioinformatics support throughout the study
  • Review your data in real time using a secure online client account

Focused Screening Panels

Our OmniScreen cancer cell line panels include:

  • OmniPanel™, a genomically diverse and growing collection of more than 500 cancer cell lines for drug response screening

  • XenoSelect™, a diverse oncogenic in vitro screening panel of more than 150 well validated cell lines with corresponding xenograft models ready for in vivo efficacy studies

  • RNAseq Panel, more than 170 in-house genomically characterized cell lines to correlate mutation status, copy number variation, and expression levels with drug response.

  • PrimePanelTM, unique cell lines derived from our patient-derived xenograft (PDX) models.

Progress your Lead Compound to Validated Candidate with CrownBio’s Expanded OmniScreen™

Enroll by June 15th, 2018

OmniScreen is a reliable, large scale in vitro screen, which allows you to take advantage of CrownBio's quarterly revival of all 500+ cancer cell lines, providing you significant cost savings.

Highlights of OmniScreen:

  • High throughput screening of at least 50 cell lines per run to maximize your savings
  • Positive drug control and cell line revival costs are included as part of OmniScreen
  • Unique subpanels built from CrownBio’s proprietary menu of 500+ cancer cell lines
    • XenoSelect™ Panel of cell lines with paired xenograft models available to accelerate your transition to in vivo studies
    • RNAseq Panel of cell lines with in-house NGS data.
    • PrimePanel of unique cell lines derived from our patient derived xenograft (PDX) models.

  • Enhanced cell line growth data for improved screening quality including:
    • Validated seeding densities across multiple time points

Request OmniScreen Pricing



Quick Facts

Posters

  • AACR 2015 1038 - Cell-based Screening Identifes Gene Expression Signature Correlated with Sensitivity to PI3KmTOR Dual Inhibitor BEZ235
  • AACR 2014 3440 - Cell-based Screening Identifies Gene Expression Signature Correlated with Sensitivity to MEK Inhibitor Trametinib

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