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MuScreen™

Screen your compound across well validated panels of Syngeneic and Tumor Homograft models to accelerate your drug development

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High Throughput In Vivo Screens for Evaluating Immunotherapies

The MuScreen platform is the only high throughput in vivo screen to evaluate immune modulating agents across preselected panels of well-characterized syngeneic and tumor homograft (MuPrime™) models.

This screen provides a cost effective and time efficient way to fast-track in vivo preclinical immunotherapy development.

Choose MuScreen to:

  • Quickly identify responder models or markers saving time and improving efficiency
  • Evaluate the efficacy of your compound across well-characterized syngeneic and tumor homograft models
  • Investigate pharmacodynamic (PD) effects using our syngeneic model panels
  • Benefit from CrownBio covering the cost of the vehicle group for all models
  • Benefit from a discount on shared control groups

Select the Models and Study Design To Suit Your Program

Model Type Model  Features
Efficacy PD
US
China
US
China
Syngeneic Display immune heterogeneity and diversity observed in the clinic
6
models
12
models
 
12
models
Tumor Homograft   Transplants of GEMM tumors into a syngeneic host, preserving original GEMM tumor molecular and histopathology and clinically relevant oncogenic driver mutations  
6
models
   

MuScreen Schedules  

Syngeneic Model Panel  

Tumor Homograft Model Panel

Efficacy and PD Mode  

Access MuBase® Database