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Model Information:

This model was developed from a tumor in the duodenum of a C57BL/6 mouse carrying a KrasLSL-G12D/WT;p53KO/KO mutation through CBD (common bile duct) injection of adeno-cre. The mouse developed a tumor in the duodenum and a tumor in the suture position approximately 8 weeks after virus injection. Kras (G12D) mutation was detected by RNAseq in both of these two tumors.
Cancer Type Sarcoma
Mutations Kras (G12D); P53-/-
Biopsy Site Duodenum
Pathology QC Undifferentiated sarcoma (Pa, P5)
Mouse Strain C57BL/6

Growth Characteristics

Additional Characteristics

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