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NAFLD/NASH

Progress your NAFLD/NASH preclinical research with CrownBio’s unique translational models
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Understand the Pathophysiology of NAFLD/NASH with CrownBio Translational Models and Services

Nonalcoholic fatty liver disease (NAFLD)/steatohepatitis (NASH) is one of the most common causes of chronic liver disease and is a major public health problem worldwide.

  • NAFLD is more common among patients with obesity and Type 2 diabetes (T2D)

  • Affects up to 70% of patients

  • Clinical diagnosis still relies on invasive and costly liver biopsy

  • Results can be unreliable and lead to complications in fragile patients

CrownBio's models of NAFLD/NASH can help elucidate the pathophysiology for:

  • Improved diagnosis

  • Developing a greater understanding of disease progression

  • Studying promising candidates in the treatment of disease