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Esophageal Cancer PDX Models

Esophageal cancer is the 6th most common cause of cancer-related deaths which drives a need for a better understanding of the underlying mechanisms behind the disease through preclinical models. Patient-derived xenograft (PDX) models provide a true representation of human heterogeneity and can be used to better understand these mechanisms in relation to the development of new therapies. Crown Bioscience has a large selection of well-characterized esophageal cancer PDX models, including models with EGFR amplification. More

PDX offer the most translational preclinical model for efficacy screening in cancer drug development. Derived directly from patient tumors and never adapted to grow in vitro, PDX models reflect the heterogeneity and diversity of the human patient population. PDX give you an accurate, predictive model of how your treatment will perform, well before entering into expensive clinical trials. Crown Bioscience's HuPrime® PDX models are well characterized for pathology, growth characteristics, and are also genetically/genomically annotated for gene expression, gene copy number, mutations, and fusions.

MODEL NUMBER CANCER SUBTYPE # per page
ES0026 ESCC CLICK TO VIEW
ES0042 ESCC CLICK TO VIEW
ES0110 ESCC CLICK TO VIEW
ES0136 ESCC CLICK TO VIEW
ES0141 ESCC CLICK TO VIEW
ES0147 ESCC CLICK TO VIEW
ES0148 ESCC CLICK TO VIEW
ES0159 ESCC CLICK TO VIEW
ES0168 ESCC CLICK TO VIEW
ES0172 ESCC CLICK TO VIEW
ES0176 ESCC CLICK TO VIEW
ES0178 ESCC CLICK TO VIEW
ES0181 CLICK TO VIEW
ES0183 EAC CLICK TO VIEW
ES0184 ESCC CLICK TO VIEW
ES0189 ESCC CLICK TO VIEW
ES0190 ESCC CLICK TO VIEW
ES0191 ESCC CLICK TO VIEW
ES0195 ESCC CLICK TO VIEW
ES0199 ESCC CLICK TO VIEW
ES0201 ESCC CLICK TO VIEW
ES0204 ESCC CLICK TO VIEW
ES0212 ESCC CLICK TO VIEW
ES0214 ESCC CLICK TO VIEW
ES0215 Sarcoma CLICK TO VIEW
ES0218 ESCC CLICK TO VIEW
ES0219 ESCC CLICK TO VIEW
ES0630 ESCC CLICK TO VIEW
ES10081 NA CLICK TO VIEW
ES10082 NA CLICK TO VIEW
ES10084 NA CLICK TO VIEW
ES10086 NA CLICK TO VIEW
ES11061 NA CLICK TO VIEW
ES11062 NA CLICK TO VIEW
ES11063 ADC CLICK TO VIEW
ES11065 NA CLICK TO VIEW
ES11068 NA CLICK TO VIEW
ES11069 NA CLICK TO VIEW
ES11072 NA CLICK TO VIEW
ES11073 ADC CLICK TO VIEW
ES11074 ADC CLICK TO VIEW
ES11075 NA CLICK TO VIEW
ES11077 NA CLICK TO VIEW
ES11079 NA CLICK TO VIEW
ES11082 NA CLICK TO VIEW
ES11085 NA CLICK TO VIEW
ES11086 NA CLICK TO VIEW
ES11087 NA CLICK TO VIEW
ES11088 ADC CLICK TO VIEW
ES11091 NA CLICK TO VIEW
ES16021 NA CLICK TO VIEW
ES2116 EAC CLICK TO VIEW
ES2263 ESCC CLICK TO VIEW
ES2267 ESCC CLICK TO VIEW
ES2311 ESCC CLICK TO VIEW
ES2356 ESCC CLICK TO VIEW
ES2411 EAC, ESCC CLICK TO VIEW
ES2563 NA CLICK TO VIEW
ES3431 ESCC CLICK TO VIEW
ES3862 ESCC CLICK TO VIEW
ES3863 ESCC CLICK TO VIEW
ES3864 NA CLICK TO VIEW
ES3865 NA CLICK TO VIEW
ES3867 NA CLICK TO VIEW
ES3872 NA CLICK TO VIEW
ES3879 ESCC CLICK TO VIEW
ES3885 ESCC CLICK TO VIEW
ES3892 NA CLICK TO VIEW
ES3894 NA CLICK TO VIEW
ES3903 NA CLICK TO VIEW
ES3904 NA CLICK TO VIEW
ES3908 NA CLICK TO VIEW
ES3910 NA CLICK TO VIEW
ES6463 ESCC CLICK TO VIEW
ES6470 NA CLICK TO VIEW
ES6824 ESCC CLICK TO VIEW
ES9291 NA CLICK TO VIEW

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