American Association for Cancer Research® (AACR) 2025 Posters

418

Assessment of PARP Inhibitor Sensitivity Through Organoid Panel Screening and Resistance Modeling Using CRISPR/Cas9 Genome Engineering

Session Category: Experimental and Molecular Therapeutics
Author: Lenno Krenning

1272

Development of PDX Models from Clinical Precision Treatment of Sacituzumab Govitecan-Resistant Breast Cancer Patient for Next-Generation Therapy Evaluation

Session Category: Tumor Biology
Author: Qingzhi Liu

5005

Integrative Multi-omics Characterization of Mouse Syngeneic Models

Session Category: Bioinformatics / Computational Biology / Systems Biology / Convergent Science
Author: Zihan Xu

5195

Development of Paired PDX-PDXO Preclinical Models for HER2-Targeting ADC Efficacy Evaluation

Session Category: Tumor Biology
Author: Jinxi Wang

5493

3D Bone Marrow Niche: Scalable and Physiologically Relevant Ex Vivo Drug Screening Platform for Hematological Malignancies

Session Category: Experimental and Molecular Therapeutics
Author: Talita Stessuk

5497

Trodelvy Screening in a Large Organoid Panel Reveals the Importance of Functional Assays for Predicting Tumor Response

Session Category: Experimental and Molecular Therapeutics
Author: Marten Hornsveld

5524

Developing KRAS G12C Inhibitor–resistant Tumor Models for Efficacy Evaluation of Next-generation Anticancer Therapies

Session Category: Experimental and Molecular Therapeutics
Authors: Jian Feng, Jun Zhou

7270

Novel Humanized Cell and Murine Models Expressing Tumor Associated Antigens for ADC Toxicity and IO Combination Evaluation

Session Category: Immunology
Author: Sylvia Wang

7274

A Preclinical In Vitro Platform for Evaluating the Potency of Bispecific T Cell Engager in 2D and 3D Models

Session Category: Immunology
Authors: Xuefei Yan, Jun Zhou

7335

Comparison of ADCC-Mediated Efficacy of CLDN18.2 mAb Zolbetuximab in hCD16A - CB17SCID HuGEMM Mice and CB17SCID Mice Bearing the SUN-6011 Tumor Model

Session Category: Immunology
Author: Lily Wang