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An Old Need for New Therapies in CLL

Chronic lymphocytic leukemia (CLL) is a cancer type mainly seen in elderly people, with the average age of diagnosis being 72 years old. However, elderly patients have been underrepresented in CLL clinical trials, and the current gold standard treatment of chemoimmunotherapy is only viable for physically fit people under 65, which rules out the majority… Read more »

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Finding the Right Path in Lung Cancer Therapy

Lung cancer is the biggest cancer killer worldwide, with historically low survival rates and a high number of cases caused by smoking. With targeted therapies now greatly improving treatment options, research is needed to uncover all of the mechanisms and oncogenes which are driving lung cancer forward. Newly published research has identified novel mutations that… Read more »

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Guiding the Way in Preclinical Radiation Research

Radiotherapy is a common treatment for many cancer types, and in recent years has become extremely effective using image guided techniques. However, preclinical irradiation models had fallen behind, with a lack of methods that were comparable to clinical treatments. The game changing small animal radiation research platform (SARRP) from Xstrahl has been turning this around,… Read more »

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FGF1 Injects Fresh Ideas into Type 2 Diabetes Research

Type 2 diabetes cannot be cured and is managed by a regimen of exercise, diet, and drugs. As the currently available treatments have a raft of side effects, including weight gain and blood sugar dropping to dangerously low levels, new therapies are needed to control the disease with fewer complications. Some impressive preclinical data were… Read more »

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Putting All Your Cancer Types in One Basket

Traditional clinical trial design in oncology of grouping together patients based on their cancer type has a high attrition rate, with an estimated 95% of potential anticancer drugs failing during development. Researchers are constantly working on ways to overcome this, and one method which is gaining popularity is a “basket” study, grouping together patients by… Read more »