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Opportunity Knocks for Oncology Clinical Trials

Patient participation in oncology clinical trials is very low due to patient concerns including worries over experimental drug effectiveness and uncertainty around joining clinical trials versus using a standard therapy. New methods are needed to encourage higher enrolment, one of which is ‘window of opportunity trials’ which use gaps in early standard of care treatment… Read more »

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The Ups and Downs of an Angiogenesis Inhibitor

Targeted therapies can often be used in multiple different cancer types, dependent on multiple cancers all having the same target, such as an upregulated or overexpressed protein, or all having the same mutation. One example of this is VEGF and VEGF receptor (VEGFR) inhibitors, which act as antiangiogenic agents and block the formation of new… Read more »

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Stem Cells – The First Step Towards a Cure for Type 1 Diabetes?

Type 1 diabetes has recently been the focus of forward thinking research, embracing technological and scientific advances to find new and innovative treatment options. Now, stem cell research has taken the first steps toward finding a potential cure for this chronic and life-altering disease.

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Spotting the Early Signs of Pancreatic Cancer

Pancreatic cancer is usually diagnosed at a late stage, which has resulted in the disease having particularly poor survival rates around the world. Finding methods to allow earlier detection and treatment could massively improve patient survival, and are a hot research topic in the field. A recent study investigating altered metabolism in pancreatic adenocarcinoma patients… Read more »

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Leukemia: A New Target for PARP Inhibitors?

Many agents in cancer research target specific molecules or pathways, meaning they are only effective in a certain subset of patients. Finding another use for an already developed drug can cut down on early stage research and offer new hope to other patient groups. This could be happening soon in leukemia, where preclinical research has… Read more »