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Obesity Linked To Self-Eating Beige Fat

Humans, like all mammals, have two types of fat with completely opposite functions: white, which stores energy and when present in excess is linked with diabetes and obesity; and brown, which produces heat by burning energy and is associated with leanness. Recently, a third type of fat was discovered within white fat, called beige fat…. Read more »

girl-child

ALL About Leukemia for Childhood Cancer Month

September is Childhood Cancer Awareness Month, raising awareness and providing time for discussion on this deadly group of diseases. A newly published set of data, which we expect to be a key talking point among specialists this month, is hoping to help accurately predict how recurrent childhood leukemia is likely to respond to further treatment.

3D glasses

Put Your Glasses On, Tumor Pharmacology Goes 3D

Attrition rates in oncology drug development are higher than in other disease areas, with almost 95% of compounds showing preclinical activity failing to reach clinical development. This indicates a disconnect between current preclinical models and tumors in patients. CrownBio, in collaboration with the University of Nottingham, has recently developed a system for growing patient-derived tumor… Read more »

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Study Finds Perfect Therapeutic Match To Fight a Common Form of Leukemia

Acute lymphoblastic leukemia (ALL) is the most common type of childhood cancer, characterized by an excessive production of immature white blood cells (lymphoblasts) by the bone marrow. Although most children survive ALL, many suffer late or long-term side effects from treatment, including heart problems, growth and development delays, secondary cancers, and infertility. Now researchers at… Read more »