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Model Information:

Synonym: RM1 RM-1 is a murine prostate cancer cell line derived from a Ras+Myc-induced prostate cancer that developed from a urogenital sinus mouse prostate reconstitution in male C57BL/6 mice(1). The model is suited for the efficacy and PD evaluation of immuno-oncology agents. At CrownBio, the RM-1 model is available as a subcutaneous model.
Cancer Type Prostate Cancer
Mouse Strain C57BL/6

Response to Immune Checkpoint Inhibitors

Additional Characteristics

(1) Thompson TC, et al. Multistage carcinogenesis induced by ras and myc oncogenes in a reconstituted organ. Cell 56(6): 917-930, 1989.

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