mPR6065
Model Information:
This strain carries a conditional mutant constitutive deletion of Trp53 and conditional knock out of PTEN (PTENflox/flox). PTEN was knocked out upon injecting adeno-cre to the prostate at 6 weeks of age, which resulted in a prostate tumor ~4 months later.
| Summary | |
|---|---|
| Cancer Type | Prostate Cancer |
| Mutations | PTENFlox/Flox; P53-/- |
| Biopsy Site | Prostate |
| Pathology QC | LipoSA-Sarcoma (P2) |
| Mouse Strain | C57BL/6 |
