mPA6114
Model Information:
This strain carries a conditional mutant Kras (KrasLSL-G12D/WT), a constitutive deletion of Trp53 (p53KO/KO) and a Cre driven by the promoter of Pdx1 gene. The mouse developed a severe pancreatic tumor and was near death at the age of 8 weeks.
| Summary |
|
| Cancer Type |
Pancreatic Cancer |
| Mutations |
KRAS (G12D); P53-/-;Pdx-1 cre |
| Biopsy Site |
Pancreases |
| Pathology QC |
Moderately differentiated adenocarcinoma (P5, Pa) |
| Mouse Strain |
C57BL/6 |
Growth Characteristics
Additional Characteristics
