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mPA6114

Model Information:

This strain carries a conditional mutant Kras (KrasLSL-G12D/WT), a constitutive deletion of Trp53 (p53KO/KO) and a Cre driven by the promoter of Pdx1 gene. The mouse developed a severe pancreatic tumor and was near death at the age of 8 weeks.
Summary  
Cancer Type Pancreatic Cancer
Mutations KRAS (G12D); P53-/-;Pdx-1 cre
Biopsy Site Pancreases
Pathology QC Moderately differentiated adenocarcinoma (P5, Pa)
Mouse Strain C57BL/6

Growth Characteristics

Additional Characteristics

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