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Model Information:

This strain carries a conditional mutant KRAS (G12D) and a conditional knockout PTEN (PTENflox/flox).
Cancer Type Lung Cancer
Mutations KRAS (G12D); PtenFlox/Flox
Biopsy Site Lung
Pathology QC Poorly differentiated adenocarcinoma with papillary adenocarcinoma structure (PA), moderately to poorly differentiated adenocarcinoma (P4), moderately differentiated adenocarcinoma (P5)
Mouse Strain C57BL/6

Growth Characteristics

Additional Characteristics

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