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mLU6073

Model Information:

This strain carries a conditional mutant constitutive deletion of Trp53 and a conditional knock out of PTEN (PTENflox/flox). The mouse was injected with adeno-cre in the prostate at 6 weeks of age. The mouse unexpectedly developed lung cancer ~4 months after the virus administration instead of prostate cancer.
Summary  
Cancer Type Lung Cancer
Mutations PTENFlox/Flox; P53-/-
Biopsy Site Lung
Pathology QC Osteosarcoma (Pa, P1)
Mouse Strain C57BL/6

Growth Characteristics

Additional Characteristics

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