mLU6054
Model Information:
This strain carries a conditional mutant Kras (KrasLSL-G12D/WT) and a conditional knock out of PTEN (PTENflox/flox). G12D mutant Kras was activated and PTEN was knocked out upon administrating adeno-cre to the lung by inhalation at 6 weeks of age, which resulted in lung cancer approximately 8 weeks later.
| Summary |
|
| Cancer Type |
Lung Cancer |
| Mutations |
KRAS (G12D); PtenFlox/Flox |
| Biopsy Site |
Lung |
| Pathology QC |
Moderately differentiated adenocarcinoma (P0) |
| Mouse Strain |
C57BL/6 |
Growth Characteristics
Additional Characteristics
