mLU6045
Model Information:
This strain carries a conditional mutant Kras (KrasLSL-G12D/WT) and a constitutive deletion of Trp53 (p53KO/KO). G12D mutant Kras was activated upon administrating adeno-cre to the lung by inhalation at 6 weeks of age, which resulted in lung cancer approximately 8 weeks later.
| Summary |
|
| Cancer Type |
Lung Cancer |
| Mutations |
Kras (G12D); P53-/- |
| Biopsy Site |
Lung |
| Pathology QC |
Poorly to moderately differentiated adenocarcinoma (Pa, P5) |
| Mouse Strain |
C57BL/6 |
| TMA |
TMA-MP-MX-001 |
Growth Characteristics
Additional Characteristics
