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mBN6091

Model Information:

This strain carries a conditional mutant Kras (KrasLSL-G12D/WT) and a conditional knock out of PTEN (PTENflox/flox). G12D mutant Kras was activated and PTEN was knocked out upon administrating the adeno-cre virus, which resulted in a tumor in the brain approximately 6 months later.
Summary  
Cancer Type Brain Cancer
Mutations KRAS (G12D); PtenFlox/Flox
Biopsy Site Brain
Pathology QC Glioblastoma (P1)
Mouse Strain C57BL/6

Growth Characteristics

Additional Characteristics

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