mBN6091
Model Information:
This strain carries a conditional mutant Kras (KrasLSL-G12D/WT) and a conditional knock out of PTEN (PTENflox/flox). G12D mutant Kras was activated and PTEN was knocked out upon administrating the adeno-cre virus, which resulted in a tumor in the brain approximately 6 months later.
| Summary | |
|---|---|
| Cancer Type | Brain Cancer |
| Mutations | KRAS (G12D); PtenFlox/Flox |
| Biopsy Site | Brain |
| Pathology QC | Glioblastoma (P1) |
| Mouse Strain | C57BL/6 |
