mBL6078
Model Information:
This strain carries a conditional mutant Kras (KrasLSL-G12D/WT) and a conditional knock out of PTEN (PTENflox/flox). G12D mutant Kras was activated and PTEN was knocked out upon administrating the adeno-cre virus to the bladder at 6 weeks of age, which resulted in a tumor in the bladder approximately 4 months later.
| Summary |
|
| Cancer Type |
Bladder Cancer |
| Mutations |
KRAS (G12D); PtenFlox/Flox |
| Biopsy Site |
Bladder (near the suture) |
| Pathology QC |
Synovial sarcoma (Pa) |
| Mouse Strain |
C57BL/6 |
Growth Characteristics
Additional Characteristics
