GA2157
Model Information:
Moderately-poorly differentiated adenocarcinoma of gastric antrum, with part of signet ring cell carcinoma, ulcerative type, tumor mass: 5.0 x 5.0cm. The tumor invade through gastric wall to serosa of pancreas and gallbladder. Regional LN: NO.1 LN (6/8), NO.3 LN (14/17), NO.5 LN (2/2), NO.6 LN (2/2), NO.7 LN (4/6), NO.4D LN (10/11), NO.8 LN (1/2). IHC results: CD44(+), cMet(weak +), EGFR(+), HER2(3+), Ki-67(+50-75%), MMP7(-), P170(-), P27(+50-75%), P53(+>75%), TOPOII(-).
| Summary |
|
| Cancer Type |
Gastric Cancer |
| Grade |
IIIC |
| Stage |
T4N2M0,IIIb |
| Ethnicity |
Asian |
| Gender |
M |
| Age |
49 |
| Pathology Diagnosis |
Moderately-poorly differentiated adenocarcinoma of gastric antrum, with part of signet ring cell carcinoma, ulcerative type, tumor mass: 5.0 x 5.0cm. The tumor invade through gastric wall to serosa of pancreas and gallbladder. Regional LN: NO.1 LN (6/8), NO.3 LN (14/17), NO.5 LN (2/2), NO.6 LN (2/2), NO.7 LN (4/6), NO.4D LN (10/11), NO.8 LN (1/2). IHC results: CD44(+), cMet(weak +), EGFR(+), HER2(3+), Ki-67(+50-75%), MMP7(-), P170(-), P27(+50-75%), P53(+>75%), TOPOII(-). |
| Biopsy Site |
primary |
| Treatment History |
SOX 2 cycles. Pathology QC: Pa-Mucinous adenocarcinoma; P2-Poorly differentiated adenocarcinoma. |
| Pathology QC |
Mucinous adenocarcinoma (Pa), poorly differentiated adenocarcinoma (P2) |
| Special Features |
Orthotopic ; ERBB2 amplified |
| Mouse Strain |
Balb/c nu |
| TMA |
TMA-HP-GA-021 |
| Viral Status in PDX |
NA |
| Available In |
CB_CN |
| RNA Seq |
P2 |
| Exome Seq |
P3 |
Growth Characteristics
Additional Characteristics
