ES2116
Model Information:
Adenocarcinoma derived from juncture of stomach and esophagus, protruded type, moderately-poorly differentiated, tumor mass: 4cm x 3.5cm. No malignant cells adjacent to esophageal stump and duodenal stump. Regional LN: right cardial LN (0/1), left cardial LN (5/5), LN of lesser curvature (0/5), inferior pyloric LN (0/4), LN of left gastric artery (3/5). IHC results: CD44(+), Cmet(+), EGFR(-), HER2(2+), Ki-67(+50-75%), MMP7(-), P170(weak +), P27(+>75%), P53(-), TOPOII(+25-50%)
| Summary |
|
| Cancer Type |
Esophageal Cancer |
| Grade |
IIIC |
| Stage |
T4N1M0,IIIa |
| Ethnicity |
Asian |
| Gender |
F |
| Age |
63 |
| Pathology Diagnosis |
Adenocarcinoma derived from juncture of stomach and esophagus, protruded type, moderately-poorly differentiated, tumor mass: 4cm x 3.5cm. No malignant cells adjacent to esophageal stump and duodenal stump. Regional LN: right cardial LN (0/1), left cardial LN (5/5), LN of lesser curvature (0/5), inferior pyloric LN (0/4), LN of left gastric artery (3/5). IHC results: CD44(+), Cmet(+), EGFR(-), HER2(2+), Ki-67(+50-75%), MMP7(-), P170(weak +), P27(+>75%), P53(-), TOPOII(+25-50%) |
| Biopsy Site |
Esophagus |
| Treatment History |
NA |
| Pathology QC |
Moderately to poorly differentiated adenocarcinoma (P1, P6) |
| Special Features |
slight BW loss, ERBB2 amplified; FGFR1 slightly amplified (6) |
| Mouse Strain |
Balb/c nu |
| TMA |
TMA-HP-ES-014 |
| Viral Status in PDX |
NA |
| Available In |
CB_CN |
| RNA Seq |
P4 |
| Exome Seq |
NA |
Growth Characteristics
Additional Characteristics
