CR2545
Model Information:
Adenocarcinoma of ascending colon, ulcerative type, poorly differentiated, invade through intestinal wall to peripheric adipose tissue. No malignant cells adjacent to superior and inferior stump. Regional LN: paraintestinal LN (0/17). IHC results: CK7(+/-), CK20(++), Syn(+++), CD56(-), Ki-67(60%+), CerbB-2(-), VEGF(-), D2-40(lymphatic vessel +).
| Summary |
|
| Cancer Type |
Colorectal Cancer |
| Grade |
NA |
| Stage |
NA |
| Ethnicity |
Asian |
| Gender |
F |
| Age |
82 |
| Pathology Diagnosis |
Adenocarcinoma of ascending colon, ulcerative type, poorly differentiated, invade through intestinal wall to peripheric adipose tissue. No malignant cells adjacent to superior and inferior stump. Regional LN: paraintestinal LN (0/17). IHC results: CK7(+/-), CK20(++), Syn(+++), CD56(-), Ki-67(60%+), CerbB-2(-), VEGF(-), D2-40(lymphatic vessel +). |
| Biopsy Site |
primary |
| Treatment History |
NA |
| Pathology QC |
Poorly differentiated adenocarcinoma (Pa, P3). |
| Special Features |
slight BW loss, CCDC6-RET fusion; Ponatinib-resistant variant of CR2518; Ulceration |
| Mouse Strain |
Balb/c nu |
| TMA |
TMA-HP-CR-030 |
| Viral Status in PDX |
EBV+ (P10, RNAseq) |
| Available In |
CB_CN |
| RNA Seq |
P10 |
| Exome Seq |
P14 |
Growth Characteristics
Additional Characteristics
