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CR2519

Model Information:

Moderately differentiated adenocarcinoma of rectum, ulcerative type, tumor mass: 3.0 x 2.5cm. The tumor invade through intestinal wall to peripheral intestinal adipose tissue (T3). Regional LN: paraintestinal LN 4/13. IHC results: CD44(+), cMet(+), COX2(+), EGFR(+), HER2(-), Ki-67(+>75%), MLH1(+>75%), MMP7(weak +<25%), MSH2(-), MSH6(+>75%), P170(+), P27(+), P53(-), TOPOII(+<25%).
Summary  
Cancer Type Colorectal Cancer
Grade IIIB
Stage T3N1M0, IIIb
Ethnicity Asian
Gender F
Age 42
Pathology Diagnosis Moderately differentiated adenocarcinoma of rectum, ulcerative type, tumor mass: 3.0 x 2.5cm. The tumor invade through intestinal wall to peripheral intestinal adipose tissue (T3). Regional LN: paraintestinal LN 4/13. IHC results: CD44(+), cMet(+), COX2(+), EGFR(+), HER2(-), Ki-67(+>75%), MLH1(+>75%), MMP7(weak +<25%), MSH2(-), MSH6(+>75%), P170(+), P27(+), P53(-), TOPOII(+<25%).
Biopsy Site Rectum
Treatment History NA
Pathology QC Moderately differentiated adenocarcinoma (P3).
Special Features Cachexia
Mouse Strain Balb/c nu
TMA TMA-HP-CR-033
Viral Status in PDX NA
Available In CB_CN
RNA Seq P7
Exome Seq P4

Growth Characteristics

Additional Characteristics

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