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CR2161

Model Information:

Moderately adenocarcinoma of colon, with part of mucous adenocarcinoma, ulcerative type, tumor mass: 6.0 x 4.0cm. The tumor invade through intestinal wall but not to intestinal serosa. Regional LN: paraintestinal LN (2/19), omental LN (0/1), LN of superior and root mesenteric artery (0/2), LN of middle colic artery (0/1). IHC results: CD44(+), cMet(+), COX2(+), EGFR(+), HER2(1+), Ki-67(+25-50%), MLH1(-), MMP7(+<25%), MSH2(+<25%), MSH6(+>75%), P170(+), P27(+<25%), P53(+<25%), TOPOII(+<25%).
Summary  
Cancer Type Colorectal Cancer
Grade IV
Stage T4N2M1,IV
Ethnicity Asian
Gender M
Age 50
Pathology Diagnosis Moderately adenocarcinoma of colon, with part of mucous adenocarcinoma, ulcerative type, tumor mass: 6.0 x 4.0cm. The tumor invade through intestinal wall but not to intestinal serosa. Regional LN: paraintestinal LN (2/19), omental LN (0/1), LN of superior and root mesenteric artery (0/2), LN of middle colic artery (0/1). IHC results: CD44(+), cMet(+), COX2(+), EGFR(+), HER2(1+), Ki-67(+25-50%), MLH1(-), MMP7(+<25%), MSH2(+<25%), MSH6(+>75%), P170(+), P27(+<25%), P53(+<25%), TOPOII(+<25%).
Biopsy Site Colon
Treatment History no
Pathology QC Moderately tubular adenocarcinoma (P2)
Special Features slight BW loss, IDH1 R132H
Mouse Strain Balb/c nu
TMA TMA-HP-CR-033
Viral Status in PDX NA
Available In CB_CN
RNA Seq P2
Exome Seq P2

Growth Characteristics

Additional Characteristics

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