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Model Information:

Synonyms: B16/BL6, B16 BL6, B16BL6, B16BL-6, BL6, BL-6, B16-F10-BL6 B16-BL6 is a murine cell line of melanoma, which was derived from the B16-F10 model for its more tissue-invasive property (1). The model is useful for the efficacy and PD assessment of anti-cancer therapeutics. At CrownBio, the B16-BL6 model is available as subcutaneous and metastatic models.
Cancer Type Melanoma
Mouse Strain C57BL/6
TMA Null

Response to Immune Checkpoint Inhibitors

Additional Characteristics

(1) Poste G., Doll J., Hart I.R., Fidler I.J. In vitro selection of murine B16 melanoma variants with enhanced tissue-invasive properties. Cancer Res. 40:1636-1644, 1980.

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