Adrenocortical carcinoma is a rare disease type with a limited number of available preclinical models for the development of novel therapeutics. CrownBio's adrenal cancer tumor homografts preserve organ-specific and disease-relevant mutations such as TP53 and Ptch1 loss, making them the ideal preclinical platform for adrenal cancer in vivo drug development.
| MODEL NUMBER | ORIGINAL GEMM MUTATION | # per page |
|---|---|---|
| mAD6185 | Ptch1-/+; P53-/- | CLICK TO VIEW |
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