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Rare Cell Analysis

Sensitively detect, isolate, and characterize rare cells

rare-cell-analysis-platform

Perform Highly Sensitive Identification of Rare Cells with our Multiparameter Imaging and Analysis Platform

Current flow cytometry and real-time PCR methods lack the sensitivity required to detect rare cells. Our rare cell analyzer and picker with multi-parameter imaging and analysis tools enables you to:

  • Enhance the quality of your preclinical and clinical data by improving quantification and visualization of rare cells over current methods, with detection sensitivity of down to 2 cells with 90% recovery

  • Understand therapeutic mechanism of action and disease progression by improving rare cell differentiation accuracy at low densities

  • Take advantage of in-life and terminal samples by utilizing various sample types including suspension, blood smears, fine needle aspirates, and FFPE

  • Gain deeper biological insight by isolating single cells and tissue micro-regions for further characterization via single cell sequencing, qRT-PCR, RNAseq, ICC, FISH, and cell culture

Maximize Therapeutic Effect by Monitoring Disease Progression

Extend agent effect by monitoring rare cells of interest. Use our rare cell analysis platform with up to six imaging channels to understand:

  • Prognosis and response to therapy by counting human or mouse circulating tumor cells (CTCs) or cells expressing biomarkers of response

  • Persistence of cell therapies such as CAR-T cells, TCR-T cells, NK cells, etc.

  • Single cell characteristics



Figure 1 CTC in Mouse Blood Sample of Lung Cancer PDX Model
Detection by DAPI, CD45, and CK



Figure 2 CD19 CAR-T Cells in DLBCL Patient Blood 9 Days Post-Injection