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In Vitro

Boost oncology drug discovery with XenoBase®, featuring the largest cell line selection and exclusive 3D organoid models. Benefit from OrganoidXplore™ and OmniScreen™ for rapid, in-depth analysis.

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In Vivo

Enhance drug development with our validated in vivo models, in vitro/ex vivo assays, and in silico modeling. Tailored solutions to optimize your candidates.

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Harness your data and discover biomarkers with our top bioinformatics expertise. Maximize data value and gain critical insights to accelerate drug discovery and elevate projects.

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Accelerate innovative cancer treatments with our advanced models and precise drug screening for KRAS mutations, efficiently turning insights into clinical breakthroughs.

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EGFR

Advance translational pharmacology with our diverse pre-clinical models, robust assays, and data science-driven biomarker analysis, multi-omics, and spatial biology.

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Drug Resistance

Our suite integrates preclinical solutions, bioanalytical read-outs, and multi-omics to uncover drug resistance markers and expedite discovery with our unique four-step strategy.

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Patient Tissue

Enhance treatments with our human tumor and mouse models, including xenografts and organoids, for accurate cancer biology representation.

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Apply the most appropriate in silico framework to your pharmacology data or historical datasets to elevate your study design and analysis, and to improve your chances of clinical success.

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Integrate advanced statistics into your drug development projects to gain significant biological insight into your therapeutic candidate, with our expert team of bioinformaticians.

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CRISPR/Cas9

Accelerate your discoveries with our reliable CRISPR solutions. Our global CRISPR licenses cover an integrated drug discovery platform for in vitro and in vivo efficacy studies.

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Rely on our experienced genomics services to deliver high quality, interpretable results using highly sensitive PCR-based, real-time PCR, and NGS technologies and advanced data analytics.

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In Vitro High Content Imaging

Gain more insights into tumor growth and disease progression by leveraging our 2D and 3D fluorescence optical imaging.

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Mass Spectrometry-based Proteomics

Next-generation ion mobility mass spectrometry (MS)-based proteomics services available globally to help meet your study needs.

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Ex Vivo Patient Tissue

Gain better insight into the phenotypic response of your therapeutic candidate in organoids and ex vivo patient tissue.

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Spatial Multi-Omics Analysis

Certified CRO services with NanoString GeoMx Digital Spatial Profiling.

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Biomarker Discovery

De-risk your drug development with early identification of candidate biomarkers and utilize our biomarker discovery services to optimize clinical trial design.

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DMPK Services

Rapidly evaluate your molecule’s pharmaceutical and safety properties with our in vivo drug metabolism and pharmacokinetic (DMPK) services to select the most robust drug formulations.

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Efficacy Testing

Explore how the novel HuGEMM™ and HuCELL™ platforms can assess the efficacy of your molecule and accelerate your immuno-oncology drug discovery programs.

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Leverage our suite of structural biology services including, recombinant protein expression and protein crystallography, and target validation services including RNAi.

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Screens

Find the most appropriate screen to accelerate your drug development: discover in vivo screens with MuScreen™ and in vitro cell line screening with OmniScreen™.

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Carry out safety pharmacology studies as standalone assessments or embedded within our overall toxicological profiling to assess cardiovascular, metabolic and renal/urinary systems.

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Global CRO in California, USA offering preclinical and translational oncology platforms with high-quality in vivo, in vitro, and ex vivo models.

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Crown Bioscience Expands Distribution Network – Appoints On Target Co, Ltd. as Sales Representative in Japan to Enable Access to Translational Oncology Assets

JAPAN’S PHARMACEUTICAL AND BIOTECH DRUG DEVELOPMENT PROGRAMS GAIN EASY ACCESS AND TECHNICAL SUPPORT OF CROWNBIO’S UNIQUE TRANSLATIONAL ONCOLOGY ASSETS HUPRIME® AND HUBASE™ WITH JAPAN’S PREMIER TECHNICAL SALES ORGANIZATION ON TARGET.

Santa Clara, California (PRWEB) August 11, 2011

Crown Bioscience (CrownBio), a leading biotech company specializing in oncology and diabetes research announces today that it has signed an agreement with Japan-based On Target Co., Ltd. (On Target) appointing On Target as its official representative in Japan. This agreement permits On Target to promote, market, and broker CrownBio’s preclinical drug discovery services throughout Japan. Crown Bioscience Vice President of Business Development Laura Sailor comments that, “Our agreement with On Target will greatly increase the visibility of CrownBio’s unique and comprehensive range of oncology and diabetes services to Japan’s research community while making it more convenient than ever to integrate CrownBio’s expertise into their development programs. CrownBio has developed an excellent working relationship with On Target and has every confidence in On Target’s ability to provide our clients in Japan with the high level of customer service and support for which we are known.” “On Target is both extremely pleased and proud to represent Crown Bioscience in Japan,” says On Target Sales Director, Keiichi Yokohama, PhD. “CrownBio is clearly an established leader among drug discovery solution providers. CrownBio’s comprehensive, state-of-the-art services in oncology and diabetes offer clients exciting new options to focus and accelerate their drug development efforts. On Target truly looks forward to helping Japan’s researchers take full advantage of CrownBio’s expertise.

About Crown Bioscience Inc.

Crown Bioscience, Inc. is a leading biotech company that provides its global biopharmaceutical industry partners with innovative and integrated solutions. Leveraging on its proprietary technology platforms in structure-based drug design and translational oncology, the company pioneers a business model that addresses the critical need of the pharmaceutical industry to improve R&D productivity while minimizing risks and retaining upside. Since its inception, CrownBio has been providing value-added services to help partners to identify the most promising compounds for clinical testing, and more importantly, enable its partners to develop strategies for biomarker development and patient stratification, an effort central to developing personalized cancer therapeutics.

As a leading cancer drug discovery partner, the company has established strategic partnerships with Pfizer and other large global pharmaceutical companies and leading Chinese pharmaceutical firms. The mandate of these partnerships is to deliver oncology clinical candidates with well defined clinical development path. By deploying its full capabilities across key functional disciplines in target validation, protein engineering, fragment-based drug design, medicinal/computational chemistry, formulation, DMPK, quantitative biology, pharmacology, and biomarker discovery, the company functions as a highly efficient external drug discovery engine to complement its partners’ internal drug R&D effort. It is actively working with other biotech and pharmaceutical companies to establish similar partnerships in oncology and other disease areas.

For more information please visit our web site at www.crownbio.com

Laura Sailor – lsailor@crownbio.com +1 606 686 9330

About On Target, Co. Ltd.

On Target’s singular mission is to accelerate pre-clinical drug discovery and development by providing the Japan pharma and biotech community with rapid and seamless access to high value services and products from carefully selected international partners. With years of prior experience, On Target prides itself on its ability to support Japan’s pharma and biotech researchers with detailed product knowledge, service logistics, and round-the-clock attention to the needs of its customers.

For more information, please visit our web site at http://www.ontarget-ddss.co.jp

On Target Co., Ltd. Keiichi Yokoyama, PhD

info@ontarget-ddss.co.jp

(+81)-3-5709-7588

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