American Association for Cancer Research® (AACR) 2026 Posters

1530

Comprehensive Preclinical Evaluation of CAR-T Cell Therapeutics in Organoid-Fibroblast Co-cultures

Session Title: CAR T Cell Targets and TME Reprogramming
Session Category: Immunology
Poster Section: 7     Poster Board #: 12
Author: Nick Ren

1814

An Integrated DMPK and Bioanalytical Platform for Comprehensive Characterization of Antibody-Drug Conjugates (ADCs)

Session Title: Quantitative Pharmacology and Translational Modeling
Session Category: Experimental and Molecular Therapeutics
Poster Section: 17     Poster Board #: 2
Author: Xiaolong Tu, Kefeng Gong

2161

Paired PDX-PDXO Models Serve an Integrated Preclinical Platform for High-Throughput Payload Screening and ADC Drugs Development

Session Title: In Vivo Models 1: Mouse, Zebrafish, and Alternative Species
Session Category: Tumor Biology
Poster Section: 29     Poster Board #: 12
Author: Jinxi Wang

2177

Characterization of a Panel of PDX Models Derived from PARP Inhibitors Pretreated Breast and Ovarian Cancer Patients for Therapeutic Evaluation

Session Title: In Vivo Models 1: Mouse, Zebrafish, and Alternative Species
Session Category: Tumor Biology
Poster Section: 29     Poster Board #: 28
Author: Qingzhi Liu

2961

Developing Trastuzumab Deruxtecan-resistant Tumor Models for Efficacy Evaluation of Next-generation Anticancer Therapies

Session Title: Drug Resistance 1: Antibodies and ADCs
Session Category: Experimental and Molecular Therapeutics
Poster Section: 12     Poster Board #: 7
Author: Jian Feng

3387

Enhancing the Predictability of Human Pharmacokinetics for Antibody-Drug Conjugates (ADCs) Using an hFcRn Transgenic Mouse Platform

Session Title: Humanized Mouse Models
Session Category: Tumor Biology
Poster Section: 27     Poster Board #: 17
Author: Xiaolong Tu, Xinhe Feng

4449

Functional Organoid Screening Uncovers Target Dependency and Bystander Killing in TROP2 ADCs

Session Title: Antibody-Drug Conjugates and Linker Engineering 3
Session Category: Experimental and Molecular Therapeutics
Poster Section: 12     Poster Board #: 27
Author: Jialei Sun

4515

Clinically Relevant AML Modeling with In Vitro Bone Marrow Niche and In Vivo PDX Approaches

Session Title: Hematologic Malignancies and Novel Therapeutic Modalities
Session Category: Experimental and Molecular Therapeutics
Poster Section: 15     Poster Board #: 6
Author: Talita Stessuk

4616

Integrated Organoid Screening Approaches Enable Preclinical Assessment of Protein Degrader Efficacy and Target Engagement

Session Title: Proximity-Induced Drug Discovery 1
Session Category: Experimental and Molecular Therapeutics
Poster Section: 18     Poster Board #: 26
Author: Marten Hornsveld

7370

End-to-end In Vitro and In Vivo Evaluation of Radiopharmaceuticals in Patient-derived Models

Session Title: Biological Mechanisms of Tumor and Normal Tissue Response and Clinical Studies
Session Category: Tumor Biology
Poster Section: 26     Poster Board #: 7
Author: Bram Herpers

7540

Integrated Multi-omics Analysis Reveals Conserved Tumor-Associated Antigens (TAAs) Profiles in PDX and Organoid Models for Advancing ADC Development

Session Title: Tumor Models and Assays: In Vitro, In Vivo
Session Category: Tumor Biology
Poster Section: 32     Poster Board #: 21
Author: Xiaolong Tu

7679

High-Quality Proteomic Profiling of Patient-Derived Tumor Models Improves Translational Accuracy in Oncology Research

Session Title: Proteomics: Biomarker Discovery and Signaling Networks
Session Category: Chemistry
Poster Section: 39     Poster Board #: 3
Author: Linda Xue