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In Vitro

Boost oncology drug discovery with XenoBase®, featuring the largest cell line selection and exclusive 3D organoid models. Benefit from OrganoidXplore™ and OmniScreen™ for rapid, in-depth analysis.

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In Vivo

Enhance drug development with our validated in vivo models, in vitro/ex vivo assays, and in silico modeling. Tailored solutions to optimize your candidates.

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Tissue

Experience ISO-certified biobanking quality. Access top biospecimens from a global clinical network, annotated by experts for precise research.

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Biomarkers and Bioanalysis

Leverage our global labs and 150+ scientists for fast, tailored project execution. Benefit from our expertise, cutting-edge tech, and validated workflows for reliable data outcomes.

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Data Science and Bioinformatics

Harness your data and discover biomarkers with our top bioinformatics expertise. Maximize data value and gain critical insights to accelerate drug discovery and elevate projects.

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KRAS

Accelerate innovative cancer treatments with our advanced models and precise drug screening for KRAS mutations, efficiently turning insights into clinical breakthroughs.

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EGFR

Advance translational pharmacology with our diverse pre-clinical models, robust assays, and data science-driven biomarker analysis, multi-omics, and spatial biology.

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Drug Resistance

Our suite integrates preclinical solutions, bioanalytical read-outs, and multi-omics to uncover drug resistance markers and expedite discovery with our unique four-step strategy.

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Patient Tissue

Enhance treatments with our human tumor and mouse models, including xenografts and organoids, for accurate cancer biology representation.

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Bioinformatics

Apply the most appropriate in silico framework to your pharmacology data or historical datasets to elevate your study design and analysis, and to improve your chances of clinical success.

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Biomarker Analysis

Integrate advanced statistics into your drug development projects to gain significant biological insight into your therapeutic candidate, with our expert team of bioinformaticians.

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CRISPR/Cas9

Accelerate your discoveries with our reliable CRISPR solutions. Our global CRISPR licenses cover an integrated drug discovery platform for in vitro and in vivo efficacy studies.

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Genomics

Rely on our experienced genomics services to deliver high quality, interpretable results using highly sensitive PCR-based, real-time PCR, and NGS technologies and advanced data analytics.

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In Vitro High Content Imaging

Gain more insights into tumor growth and disease progression by leveraging our 2D and 3D fluorescence optical imaging.

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Mass Spectrometry-based Proteomics

Next-generation ion mobility mass spectrometry (MS)-based proteomics services available globally to help meet your study needs.

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Ex Vivo Patient Tissue

Gain better insight into the phenotypic response of your therapeutic candidate in organoids and ex vivo patient tissue.

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Spatial Multi-Omics Analysis

Certified CRO services with NanoString GeoMx Digital Spatial Profiling.

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Biomarker Discovery

De-risk your drug development with early identification of candidate biomarkers and utilize our biomarker discovery services to optimize clinical trial design.

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DMPK Services

Rapidly evaluate your molecule’s pharmaceutical and safety properties with our in vivo drug metabolism and pharmacokinetic (DMPK) services to select the most robust drug formulations.

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Efficacy Testing

Explore how the novel HuGEMM™ and HuCELL™ platforms can assess the efficacy of your molecule and accelerate your immuno-oncology drug discovery programs.

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Laboratory Services

Employ cutting-edge multi-omics methods to obtain accurate and comprehensive data for optimal data-based decisions.

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Pharmacology & Bioanalytical Services

Leverage our suite of structural biology services including, recombinant protein expression and protein crystallography, and target validation services including RNAi.

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Screens

Find the most appropriate screen to accelerate your drug development: discover in vivo screens with MuScreen™ and in vitro cell line screening with OmniScreen™.

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Toxicology

Carry out safety pharmacology studies as standalone assessments or embedded within our overall toxicological profiling to assess cardiovascular, metabolic and renal/urinary systems.

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Our Company

Global CRO in California, USA offering preclinical and translational oncology platforms with high-quality in vivo, in vitro, and ex vivo models.

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Our Purpose

Learn more about the impact we make through our scientific talent, high-quality standards, and innovation.

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Our Responsibility

We build a sustainable future by supporting employee growth, fostering leadership, and exceeding customer needs. Our values focus on innovation, social responsibility, and community well-being.

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Meet Our Leadership Team

We build a sustainable future by fostering leadership, employee growth, and exceeding customer needs with innovation and social responsibility.

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Scientific Advisory Board

Our Scientific Advisory Board of experts shapes our strategy and ensures top scientific standards in research and development.

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News & Events

Stay updated with Crown Bioscience's latest news, achievements, and announcements. Check our schedule for upcoming events and plan your visit.

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Career Opportunities

Join us for a fast-paced career addressing life science needs with innovative technologies. Thrive in a respectful, growth-focused environment.

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Scientific Publications

Access our latest scientific research and peer-reviewed articles. Discover cutting-edge findings and insights driving innovation and excellence in bioscience.

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Resources

Discover valuable insights and curated materials to support your R&D efforts. Explore the latest trends, innovations, and expertly curated content in bioscience.

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Blogs

Explore our blogs for the latest insights, research breakthroughs, and industry trends. Stay educated with expert perspectives and in-depth articles driving innovation in bioscience.

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Patient-Derived Xenograft (PDX) Tumor Microarrays (TMAs)

Enhancing Cancer Research with High-Throughput PDX TMAs

At Crown Bioscience, our Patient-Derived Xenograft (PDX) Tumor Microarrays (TMAs) offer researchers a powerful tool for cancer research, enabling high-throughput analysis of various cancer types. Our PDX TMAs provide an extensive array of tissue samples crucial for biomarker validation, drug target discovery, and translational research.

Our PDX TMA Catalog Includes:

NAME CATALOG #
Bladder Cancer TMA046 TMA-HP-BL-046
Breast Cancer TMA040 TMA-HP-BR-040
Breast Cancer TMA050 TMA-HP-BR-050
Colorectal cancer PDX TMA019 TMA-HP-CR-019
Colorectal cancer PDX TMA025 TMA-HP-CR-025
Colorectal cancer PDX TMA026 TMA-HP-CR-026
Colorectal cancer PDX TMA030 TMA-HP-CR-030
Colorectal cancer PDX TMA033 TMA-HP-CR-033
Colorectal cancer PDX TMA038 TMA-HP-CR-038
Colorectal Cancer PDX TMA045 TMA-HP-CR-045
Cervical Cancer TMA047 TMA-HP-CV-047
Esophageal cancer PDX TMA014 TMA-HP-ES-014
Gastric cancer PDX TMA034 TMA-HP-GA-034
Gastric cancer PDX TMA053 TMA-HP-GA-053
Gastric cancer PDX TMA055 TMA-HP-GA-055
Leukemia & Lymphoma TMA035 TMA-HP-HK-035
Head and neck cancer PDX TMA024 TMA-HP-HN-024
Head & Neck cancer PDX TMA031 TMA-HP-HN-031
Kidney Cancer TMA049 TMA-HP-KI-049
Liver cancer PDX TMA028 TMA-HP-LI-028
Liver cancer PDX TMA052 TMA-HP-LI-052
Lung cancer PDX TMA015 TMA-HP-LU-015
Lung cancer PDX TMA017 TMA-HP-LU-017
Lung cancer PDX TMA022 TMA-HP-LU-022
Lung cancer PDX TMA032 TMA-HP-LU-032
Lung Cancer PDX TMA043 TMA-HP-LU-043
Lung Cancer PDX TMA044 TMA-HP-LU-044
Lung Cancer TMA048 TMA-HP-LU-048
Lung cancer PDX TMA054 TMA-HP-LU-054
Melanoma PDX TMA037 TMA-HP-ME-037
Melanoma PDX TMA041 TMA-HP-ME-041
Melanoma PDX TMA042 TMA-HP-ME-042
Ovarian cancer PDX TMA029 TMA-HP-OV-029
Pancreatic cancer PDX TMA018 TMA-HP-PA-018
Pancreatic Cancer PDX TMA027 TMA-HP-PA-027
Pancreatic cancer PDX TMA039 TMA-HP-PA-039
Sarcoma PDX TMA036 TMA-HP-SA-036

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Why Choose Crown Bioscience PDX TMAs?

  • Comprehensive Sample Collection: Extensive tumor arrays for diverse research needs.
  • High-Throughput Analysis: Efficiently analyze multiple samples simultaneously.
  • Crucial for Research: Essential for validating biomarkers and identifying drug targets.

For more information about our PDX TMAs or to discuss your research needs, please contact us.