Validated Genomic and Proteomic Biomarker Assays to Inform Drug Development
Robust analysis of study samples is important to optimize therapeutic benefit and discover biomarkers. Advance your therapeutic candidates through genomic and proteomic analysis.
- Effectively predict response and toxicity through potential candidate biomarker identification
- Enhance your pharmacology data by determining qualitative and quantitative agent effects at the genomic and proteomic level
- Maximize drug effects by comprehensively evaluating mechanism of action and PD
- Reduce potential toxicities by understanding immune and morphological composition of relevant organs
- Extend therapeutic benefit by improving monitoring of disease progression and treatment persistence
High Throughput Biomarker Assay Services
Analyze your preclinical and non-CLIA regulated clinical samples with our diverse biomarker assay service, including:
- Multi-parametric flow cytometry for immunophenotyping (standard and custom panels)
- Immunohistochemistry, high throughput imaging/analysis, and pathology
- Singleplex and multiplex ELISA-based cytokine and chemokine profiling
- Genomic analysis via highly sensitive PCR-based, real-time PCR, and NGS technologies
- Bioinformatics to guide biomarker discovery and validation, statistical analyses, and preclinical study/clinical trial design
- Rare cell analyses for detection and monitoring of CTC, CAR-T cells, etc.
- Complete blood count (preclinical samples only)
We Have Your Biomarker Assay Needs Covered
CrownBio’s available services work perfectly as either standalone or part of an end-to-end, well-integrated preclinical program:
- Improve preclinical translatability by using well-characterized, clinically relevant models
- Benefit from our long-standing experience in conducting pharmacology studies, more than 200 mouse clinical trials, and generating over 10,000 treatment data
- Simply and rapidly find models to meet your needs based on growth, response to treatment, molecular signatures, histology, and immune phenotype using our extensive databases of over 2000 oncology models
- Gain expert guidance from our global bioinformatics team who have published bioinformatics solutions in multiple peer-reviewed journals
