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Boost oncology drug discovery with XenoBase®, featuring the largest cell line selection and exclusive 3D organoid models. Benefit from OrganoidXplore™ and OmniScreen™ for rapid, in-depth analysis.
Enhance drug development with our validated in vivo models, in vitro/ex vivo assays, and in silico modeling. Tailored solutions to optimize your candidates.
Experience ISO-certified biobanking quality. Access top biospecimens from a global clinical network, annotated by experts for precise research.
Leverage our global labs and 150+ scientists for fast, tailored project execution. Benefit from our expertise, cutting-edge tech, and validated workflows for reliable data outcomes.
Harness your data and discover biomarkers with our top bioinformatics expertise. Maximize data value and gain critical insights to accelerate drug discovery and elevate projects.
Accelerate innovative cancer treatments with our advanced models and precise drug screening for KRAS mutations, efficiently turning insights into clinical breakthroughs.
Advance translational pharmacology with our diverse pre-clinical models, robust assays, and data science-driven biomarker analysis, multi-omics, and spatial biology.
Our suite integrates preclinical solutions, bioanalytical read-outs, and multi-omics to uncover drug resistance markers and expedite discovery with our unique four-step strategy.
Enhance treatments with our human tumor and mouse models, including xenografts and organoids, for accurate cancer biology representation.
Journey through the drug discovery pipeline from target discovery to in vivo pharmacology. Take advantage of the Largest biobank of patient-derived models, Model development capabilities, Cell-based assays for Screening ADCs, and advanced downstream analysis.
Apply the most appropriate in silico framework to your pharmacology data or historical datasets to elevate your study design and analysis, and to improve your chances of clinical success.
Integrate advanced statistics into your drug development projects to gain significant biological insight into your therapeutic candidate, with our expert team of bioinformaticians.
Accelerate your discoveries with our reliable CRISPR solutions. Our global CRISPR licenses cover an integrated drug discovery platform for in vitro and in vivo efficacy studies.
Rely on our experienced genomics services to deliver high quality, interpretable results using highly sensitive PCR-based, real-time PCR, and NGS technologies and advanced data analytics.
Gain more insights into tumor growth and disease progression by leveraging our 2D and 3D fluorescence optical imaging.
Next-generation ion mobility mass spectrometry (MS)-based proteomics services available globally to help meet your study needs.
Gain better insight into the phenotypic response of your therapeutic candidate in organoids and ex vivo patient tissue.
Certified CRO services with NanoString GeoMx Digital Spatial Profiling.
De-risk your drug development with early identification of candidate biomarkers and utilize our biomarker discovery services to optimize clinical trial design.
Rapidly evaluate your molecule’s pharmaceutical and safety properties with our in vivo drug metabolism and pharmacokinetic (DMPK) services to select the most robust drug formulations.
Explore how the novel HuGEMM™ and HuCELL™ platforms can assess the efficacy of your molecule and accelerate your immuno-oncology drug discovery programs.
Employ cutting-edge multi-omics methods to obtain accurate and comprehensive data for optimal data-based decisions.
Leverage our suite of structural biology services including, recombinant protein expression and protein crystallography, and target validation services including RNAi.
Find the most appropriate screen to accelerate your drug development: discover in vivo screens with MuScreen™ and in vitro cell line screening with OmniScreen™.
Carry out safety pharmacology studies as standalone assessments or embedded within our overall toxicological profiling to assess cardiovascular, metabolic and renal/urinary systems.
Learn more about how our consulting services can help to support your journey to the clinic.
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Integrated Pipeline for Immuno-Oncology Drug Testing: From Patient-Derived Organoid Assays with Reconstituted TME to Fresh Ex Vivo Patient Tissue CulturesSession Category: Immunology |
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538 |
Establishment of PARP Inhibitor-Induced Resistant Patient-Derived Ovarian Cancer Xenograft ModelsSession Category: Experimental and Molecular Therapeutics |
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1942 |
Developing KRAS G12C Inhibitor-Resistant Tumor Models for Efficacy Evaluation of Next-Generation Anticancer TherapiesSession Category: Experimental and Molecular Therapeutics |
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2827 |
Characterization of Acute Myeloid Leukemia PDX Models with Hotspot Gene Mutations for Therapeutic EvaluationSession Category: Tumor Biology |
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3515 |
SynAI: An AI-Driven Cancer Drug Synergism Prediction PlatformSession Category: Bioinformatics / Computational Biology / Systems Biology / Convergent ScienceA |
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4179 |
Magnetic Resonance Imaging and Bioluminescence Imaging for Evaluating Tumor Burden in Orthotopic GlioblastomaSession Category: Tumor Biology |
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4213 |
Multiplex Digital Spatial Profiling of Proteins and RNA in MC38 Mouse Colorectal Cancer Syngeneic ModelSession Category: Tumor Biology |
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5264 |
KRASG12C Inhibition Synergizes with Checkpoint Blockade in KRASG12C-Mutated Tumor ModelSession Category: Immunology |
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7174 |
Pharmacokinetics and Immunogenicity of Anti-PD-1 Antibody in Humanized FcRn Mouse Models Compared to Immunocompetent Mouse ModelsSession Category: Experimental and Molecular Therapeutics |
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LB435 |
Large Panel Organoid Drug Testing Combined with Biomarker Analysis: Unveiling Prospects of Mechanism of Action Identification and Preclinical Patient StratificationSession Category: N/A |
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2024-03-06
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