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In Vitro

Boost oncology drug discovery with XenoBase®, featuring the largest cell line selection and exclusive 3D organoid models. Benefit from OrganoidXplore™ and OmniScreen™ for rapid, in-depth analysis.

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In Vivo

Enhance drug development with our validated in vivo models, in vitro/ex vivo assays, and in silico modeling. Tailored solutions to optimize your candidates.

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Experience ISO-certified biobanking quality. Access top biospecimens from a global clinical network, annotated by experts for precise research.

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Biomarkers and Bioanalysis

Leverage our global labs and 150+ scientists for fast, tailored project execution. Benefit from our expertise, cutting-edge tech, and validated workflows for reliable data outcomes.

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Data Science and Bioinformatics

Harness your data and discover biomarkers with our top bioinformatics expertise. Maximize data value and gain critical insights to accelerate drug discovery and elevate projects.

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Accelerate innovative cancer treatments with our advanced models and precise drug screening for KRAS mutations, efficiently turning insights into clinical breakthroughs.

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Advance translational pharmacology with our diverse pre-clinical models, robust assays, and data science-driven biomarker analysis, multi-omics, and spatial biology.

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Drug Resistance

Our suite integrates preclinical solutions, bioanalytical read-outs, and multi-omics to uncover drug resistance markers and expedite discovery with our unique four-step strategy.

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Patient Tissue

Enhance treatments with our human tumor and mouse models, including xenografts and organoids, for accurate cancer biology representation.

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Apply the most appropriate in silico framework to your pharmacology data or historical datasets to elevate your study design and analysis, and to improve your chances of clinical success.

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Biomarker Analysis

Integrate advanced statistics into your drug development projects to gain significant biological insight into your therapeutic candidate, with our expert team of bioinformaticians.

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Accelerate your discoveries with our reliable CRISPR solutions. Our global CRISPR licenses cover an integrated drug discovery platform for in vitro and in vivo efficacy studies.

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Rely on our experienced genomics services to deliver high quality, interpretable results using highly sensitive PCR-based, real-time PCR, and NGS technologies and advanced data analytics.

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In Vitro High Content Imaging

Gain more insights into tumor growth and disease progression by leveraging our 2D and 3D fluorescence optical imaging.

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Mass Spectrometry-based Proteomics

Next-generation ion mobility mass spectrometry (MS)-based proteomics services available globally to help meet your study needs.

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Ex Vivo Patient Tissue

Gain better insight into the phenotypic response of your therapeutic candidate in organoids and ex vivo patient tissue.

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Spatial Multi-Omics Analysis

Certified CRO services with NanoString GeoMx Digital Spatial Profiling.

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Biomarker Discovery

De-risk your drug development with early identification of candidate biomarkers and utilize our biomarker discovery services to optimize clinical trial design.

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DMPK Services

Rapidly evaluate your molecule’s pharmaceutical and safety properties with our in vivo drug metabolism and pharmacokinetic (DMPK) services to select the most robust drug formulations.

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Efficacy Testing

Explore how the novel HuGEMM™ and HuCELL™ platforms can assess the efficacy of your molecule and accelerate your immuno-oncology drug discovery programs.

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Laboratory Services

Employ cutting-edge multi-omics methods to obtain accurate and comprehensive data for optimal data-based decisions.

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Pharmacology & Bioanalytical Services

Leverage our suite of structural biology services including, recombinant protein expression and protein crystallography, and target validation services including RNAi.

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Find the most appropriate screen to accelerate your drug development: discover in vivo screens with MuScreen™ and in vitro cell line screening with OmniScreen™.

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Carry out safety pharmacology studies as standalone assessments or embedded within our overall toxicological profiling to assess cardiovascular, metabolic and renal/urinary systems.

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Our Company

Global CRO in California, USA offering preclinical and translational oncology platforms with high-quality in vivo, in vitro, and ex vivo models.

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We build a sustainable future by supporting employee growth, fostering leadership, and exceeding customer needs. Our values focus on innovation, social responsibility, and community well-being.

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We build a sustainable future by fostering leadership, employee growth, and exceeding customer needs with innovation and social responsibility.

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Our Scientific Advisory Board of experts shapes our strategy and ensures top scientific standards in research and development.

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On-Demand TechTalk

Image-Based Quantification of Myeloid Cell Repolarization and their Interplay within the Tumor Microenvironment in 3D

Image-Based Quantification of Myeloid Cell Repolarization and their Interplay within the Tumor Microenvironment in 3DPresenter: Dr. Gera Goverse, Senior Scientist, Crown Bioscience

Want to progress your myeloid and TME-targeting immuno-oncology drugs with confidence? Discover the benefits of the Myeloid Repolarisation Assay in our upcoming TechTalk:

  • Visualize and quantify immunotherapy and TME effects on myeloid cells using a robust 3D phenotypic analysis

  • Analyze myeloid cells cultured in 3D better resembling the physiological environment in vivo

  • Accurately measure the functional reprogramming of the suppressive tumor-associated macrophage population towards an M1 phenotype induced by drug candidates

  • Understand drug effects in a suppressive TME in both monocultures of myeloid cells and co-cultures of myeloid cells and tumoroids with an option to include T cells through functional readouts including tumoroid killing and immune cell infiltration

In this TechTalk Dr. Gera Goverse will discuss how the incorporation of different myeloid cell populations results in a better representation of the human immune system in the tumor microenvironment (TME) in 3D image-based co-cultures of tumor and immune cells. Discover our 3D high content imaging assay to visualize and quantify immunotherapy and TME effects on myeloid cells using 3D phenotypic analysis.

Watch this webinar to explore:

  • The principles of the Myeloid Repolarisation Assay

  • Evaluation of drug-induced repolarization of myeloid cells as monoculture in 3D

  • Identify phenotypic profiles of different myeloid cell populations in 3D

  • And much more!

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About The Presenter:

Dr. Gera GoverseDr. Gera Goverse joined OcellO in 2017 and is currently Senior Scientist and head of Myeloid Cell Biology at Crown Bioscience Netherlands. Her expertise is in assay development for testing drug candidates targeting the immune cell response leading to the killing of tumors in 3D high content image assays.

Dr. Goverse who obtained her Ph.D. in Immunology at the VU Medical Centre Amsterdam and continued her post doctoral studies at the KU Leuven, applies her obtained knowledge within these complex assays studying different subsets of immune cells and is specialized in the role of the myeloid cell compartment.

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