NAFLD/NASH Mouse Model with Metabolic Dysregulation

Metabolic disturbances such as insulin resistance, obesity, and dyslipidemia are prominent risk factors in the development of non-alcoholic fatty liver disease (NAFLD). NAFLD can progress in severity from simple steatosis to non-alcoholic steatohepatitis (NASH), which can move on to cirrhosis and eventually hepatocellular carcinoma.