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Modeling Anti-Leukemic Therapy by Patient-Derived AML Xenografts with Distinct Phenotypes/Genotypes

We have recently successfully engrafted leukemic cells, isolated from bone marrows of 3 AML patients with subtypes of M5 (AM7577), M2 (AM8096) and M6 (AM8070), into immunocompromised NOD/SCID mice.