Yanrui Song, Jessie Wang, Likun Zhang, Annie X An, Henry Q.X. Li, Davy X. Ouyang
#Cyagen Biosciences Inc
Advanced preclinical models are needed for breast cancer research, to evaluate new therapeutics and to better understand tumor biology. Tumor homografts are derived from genetically engineered mouse models (GEMMs), and combine GEMM histopathological and molecular features with an improved operational efficiency and more synchronized tumor growth.
This poster details the establishment and characterization of a range of breast cancer tumor homografts from GEMMs commonly used in preclinical breast cancer research. Characterization data includes histopathological and immunohistochemical analysis, immunoprofiling, as well as benchmarking with immunotherapeutic, cytotoxic, and targeted therapies.
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2023-02-19
2021-10-25
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