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April 22-25, Boston, MA


Utility of an Accelerated Translational Model of NASH: MS-NASH Mouse Induced with High Fat Diet and CCl4

Tuesday 23 April, 11:45 AM, Translational Stream
Presented by Dr Guodong Zhang, Director of Crown Bioscience Louisiana (CBLA)

Learn more about a new NASH model with accelerated disease progression and exacerbated pathology, and its utility in preclinical NASH studies. Discover model characterization and improved outcomes following treatment with obeticholic acid.


A Comparison of Computerized Pathology Readings with Manual Readout in the Same Set of NASH MS-NASH/Pco Mouse Model Histology Images

Tuesday 23 April, 6:45 PM

Explore the relationship observed between an automated NASH analysis platform versus manual pathologist scoring of tissue from the NAFLD/NASH MS-NASH mouse model and C57BL/6 mouse, across different diets and treatments. See how automated scoring of steatosis and fibrosis correlates to pathologist analysis, and explore possible utilization and improvement of computerized results in supplement of manual readout.


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