B7-H3 Antibody

Catalog # CA001

products.png

Description

B7-H3 belongs to the immunoglobulin superfamily, and is thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Image

Western blot analysis of extracts of various cell lines, using B7-H3 antibody, catalog # CA001.

Product Details

Catalog #: CA001
Size: 100 ul
Clone ID: Polyclonal
Host species: Rabbit
Ig subclass: IgG
Immunogen: Recombinant protein of human B7-H3
UniProt ID: Q5ZPR3
Gene ID: 80381
Synonyms: CD276; B7H3; B7-H3; B7RP-2; 4Ig-B7-H3;
Calculated MW: 57 kDa
Observed MW: Refer to figure
Species Reactivity: Human, Mouse, Rat
Applications: WB, IHC, FC
Recommended dilutions: WB 1:500 - 1:2000
IHC 1:20 - 1:200
FC 1:20 - 1:50
Purification Method: Affinity purified
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles.

$275
cart.png

Ask a Question / Request a Quote

Complete the form below to receive additional information about isotype control antibodies for in vivo and in vitro studies, or call:

+1 855 827 6968
6am - 5pm (PST)