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Clarity with
Crown

Recognize your next clinical candidate when you see it.

Our Translational Platforms enable our clients to identify the right patients for the right treatment. Having models which more accurately mimic human disease and population dynamics are key to successfully translating promising compounds into successful clinical candidates, whether treating Oncology or Diabetes related diseases.

Magnify your
insights

Understand the mechanisms of disease.

Our scientific acumen and experience will give you a deeper understanding of not just the pharmacological profile of your compound, but more importantly, a clear understanding of which compounds to progress into the clinic. Take a look at our publications to get a deeper understanding of the depth of our scientific expertise.

Begin with the
end insight

Connecting science to patients.

We help our clients solve some of today's most pressing problems in oncology, cardiovascular, and metabolic disease by answering some of the most challenging questions about human biology.

CVMD

Models of Obesity

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CrownBio’s preclinical Translational Technology Platforms provide spontaneous & diet-induced obesity (DIO) models, to support the transition of new agents into the clinic.

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Oncology

Oncology Databases

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Our unique databases provide a curated source of well-characterized models available to use for drug discovery including PDX models, cell lines, and syngeneic models.

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CVMD

Diabetes Models

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Models of both Type 1 and Type 2 diabetes, including conventional, as well as unique, highly translatable models for in vivo efficacy studies of antidiabetic agents.

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Latest from our Blog

December 18, 2020

Factors to Consider When Selecting a Next Generation Sequencing (NGS) Technology

Explore the main factors you need to consider before choosing and using next generation sequencing (NGS).

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December 18, 2020

Factors to Consider When Selecting a Next Generation Sequencing (NGS) Technology

Explore the main factors you need to consider before choosing and using next generation...

Read More

December 16, 2020

Germ-Free or Antibiotic-Treated Mice? Which Model for Studying the Role of the Gut Microbiota in Preclinical Studies

Explore the differences and similarities of germ-free (GF) and antibiotic-treated mice as models...

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December 3, 2020

The Latest Developments on PARP Inhibitors for Prostate Cancer Treatment

Review the status of PARP inhibitors (PARPi) for prostate cancer treatment, with a focus on...

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November 30, 2020

The Rising Importance of GITR Agonists as Alternative I/O Candidates for Combination Drug Strategies

Explore why glucocorticoid-induced TNFR-related protein (GITR or CD357) agonists are becoming...

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November 10, 2020

SHP2 and SOS1 Targets: Additional Players in the KRAS Inhibitors Race?

Explore why upstream KRAS-mutant targets, such as SHP2 and SOS1, may lead to optimized...

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Upcoming Events


January 26-28, 2021

5th PREDiCT: Tumor Models for Immuno-Oncology 2021

Virtual