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Clarity with

Recognize your next clinical candidate when you see it.

Our Translational Platforms enable our clients to identify the right patients for the right treatment. Having models which more accurately mimic human disease and population dynamics are key to successfully translating promising compounds into successful clinical candidates, whether treating Oncology or Diabetes related diseases.

Magnify your

Understand the mechanisms of disease.

Our scientific acumen and experience will give you a deeper understanding of not just the pharmacological profile of your compound, but more importantly, a clear understanding of which compounds to progress into the clinic. Take a look at our publications to get a deeper understanding of the depth of our scientific expertise.

Begin with the
end insight

Connecting science to patients.

We help our clients solve some of today's most pressing problems in oncology, cardiovascular, and metabolic disease by answering some of the most challenging questions about human biology.


Models of Obesity


CrownBio’s preclinical Translational Technology Platforms provide spontaneous & diet-induced obesity (DIO) models, to support the transition of new agents into the clinic.

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Oncology Databases


Our unique databases provide a curated source of well-characterized models available to use for drug discovery including PDX models, cell lines, and syngeneic models.

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Diabetes Models


Models of both Type 1 and Type 2 diabetes, including conventional, as well as unique, highly translatable models for in vivo efficacy studies of antidiabetic agents.

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Latest from our Blog

August 2, 2021

In vivo preclinical models for immune-mediated inflammatory disease drug development

In this blog we will explore immune-mediated inflammatory diseases (IMIDs)—which represent a diverse group of conditions characterized by an excessive and/or inappropriate immune response. Interest in IMIDs has grown rapidly in recent years, largely fueled by the view that IMIDs share common inflammatory pathways, and therefore, there...

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July 5, 2021

Preclinical Models for Bispecific T Cell Engager Development

Last month we hosted a webinar with Dr. Ludovic Bourré, Senior Director of Scientific Engagement...

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June 1, 2021

Ask the Expert: Organoid and Immune Cell Co-Cultures

Dr Yujun Huang, Senior Director Immuno-Oncology at CrownBio, answers the most popular questions...

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May 4, 2021

For the Children: Advancing the Cause of Pediatric Cancer Research

Why are cancer treatments for children lagging behind the latest advancements in clinical...

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April 1, 2021

Expanding the Horizon of Antibody-Drug Conjugates for Cancer Treatment

This post explores the fast-expanding topic of antibody-drug conjugates (ADCs), including those...

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Upcoming Events

July 15, 2021

Advancing Authentication: Next Generation Technology for Cell Line and Biosample Verification

September 21-23, 2021

6th Annual PREDiCT: 3D Tissue Models Summit

The Colonnade Boston