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AACR 2024 Poster 87: Integrated Pipeline for Immuno-Oncology Drug Testing: From Patient-Derived Organoid...

Poster

AACR 2024 Poster 87: Integrated Pipeline for Immuno-Oncology Drug Testing: From Patient-Derived Organoid...

AACR 2024 Poster 538: Establishment of PARP Inhibitor-Induced Resistant Patient-Derived...

Poster

AACR 2024 Poster 538: Establishment of PARP Inhibitor-Induced Resistant Patient-Derived...

AACR 2024 Poster 1942: Developing KRAS G12C Inhibitor-Resistant Tumor Models for Efficacy Evaluation of...

Poster

AACR 2024 Poster 1942: Developing KRAS G12C Inhibitor-Resistant Tumor Models for Efficacy Evaluation of...

AACR 2024 Poster 2827: Characterization of Acute Myeloid Leukemia PDX Models with Hotspot...

Poster

AACR 2024 Poster 2827: Characterization of Acute Myeloid Leukemia PDX Models with Hotspot...

AACR 2024 Poster 3515: SynAI: An AI-Driven Cancer Drug Synergism Prediction Platform

Poster

AACR 2024 Poster 3515: SynAI: An AI-Driven Cancer Drug Synergism Prediction Platform

AACR 2024 Poster 4179: Magnetic Resonance Imaging and Bioluminescence Imaging for Evaluating Tumor Burden in Orthotopic Glioblastoma

Poster

AACR 2024 Poster 4179: Magnetic Resonance Imaging and Bioluminescence Imaging for Evaluating Tumor Burden in Orthotopic Glioblastoma

AACR 2024 Poster 4213: Multiplex Digital Spatial Profiling of Proteins and RNA in MC38 Mouse Colorectal Cancer Syngeneic Model

Poster

AACR 2024 Poster 4213: Multiplex Digital Spatial Profiling of Proteins and RNA in MC38 Mouse Colorectal Cancer Syngeneic Model

AACR 2024 Poster 5264: KRASG12C Inhibition Synergizes with Checkpoint Blockade in KRASG12C-Mutated Tumor Model

Poster

AACR 2024 Poster 5264: KRASG12C Inhibition Synergizes with Checkpoint Blockade in KRASG12C-Mutated Tumor Model

AACR 2024 Poster 7174: Pharmacokinetics and Immunogenicity of Anti-PD-1 Antibody in Humanized FcRn Mouse...

Poster

AACR 2024 Poster 7174: Pharmacokinetics and Immunogenicity of Anti-PD-1 Antibody in Humanized FcRn Mouse...

AACR 2024 Poster LB435: Large Panel Organoid Drug Testing Combined with Biomarker Analysis: Unveiling Prospects of...

Poster

AACR 2024 Poster LB435: Large Panel Organoid Drug Testing Combined with Biomarker Analysis: Unveiling Prospects of...

Pretreated Patient-derived Xenograft Models: A Key Tool for Developing Innovative Anticancer Therapies

White Paper

Pretreated Patient-derived Xenograft Models: A Key Tool for Developing Innovative Anticancer Therapies

SynAI: An AI-driven Cancer Drugs Synergism Prediction Platform

On-Demand Webinar

SynAI: An AI-driven Cancer Drugs Synergism Prediction Platform

A Novel Approach to Overcoming Limitations of T Cell Immunotherapies

On-Demand Webinar

A Novel Approach to Overcoming Limitations of T Cell Immunotherapies

Mini-tumors: Pre-clinical HCI assays to screen anti-cancer drugs in the context of organoids, cancer-associated fibroblasts and immune cells

Application Note

Mini-tumors: Pre-clinical HCI assays to screen anti-cancer drugs in the context of organoids, cancer-associated fibroblasts and immune cells

Assay-ready Organoid Drug Screening With Robust, Reproducible, and Clinically-relevant Output

On-Demand Webinar

Assay-ready Organoid Drug Screening With Robust, Reproducible, and Clinically-relevant Output

Effective Preclinical Solutions to Tackle Oncology Drug Resistance

On-Demand Webinar

Effective Preclinical Solutions to Tackle Oncology Drug Resistance

New Technologies, Tools, and Trends for Cancer Immunotherapy Research: A Practical Guide to an Innovative Immuno-oncology Toolbox

eBook

New Technologies, Tools, and Trends for Cancer Immunotherapy Research: A Practical Guide to an Innovative Immuno-oncology Toolbox

Large-Panel Organoid Screening: Bridging Reproducibility and Clinical Relevance in Oncology Drug Discovery

On-Demand Webinar

Large-Panel Organoid Screening: Bridging Reproducibility and Clinical Relevance in Oncology Drug Discovery

High-frequency Ultrasound Guided Injection and Monitoring of Orthotopic Murine Models

FactSheet

High-frequency Ultrasound Guided Injection and Monitoring of Orthotopic Murine Models

RNA Degradation and Its Influence on Transcriptomic Profiling: A Case Study with Preclinical Samples

On-Demand Webinar

RNA Degradation and Its Influence on Transcriptomic Profiling: A Case Study with Preclinical Samples

Functional Screening with Patient-Derived Organoids and High-Content Imaging

White Paper

Functional Screening with Patient-Derived Organoids and High-Content Imaging

OrganoidXplore™

FactSheet

OrganoidXplore™

Deep Learning Models in Preclinical Histopathology Image Analysis

On-Demand Webinar

Deep Learning Models in Preclinical Histopathology Image Analysis

SITC 2023 Poster 1119: Selective Reversal of Key Features of T Cell Exhaustion in an In Vitro Model by a SMARCA4/2 ATPase Inhibitor

Poster

SITC 2023 Poster 1119: Selective Reversal of Key Features of T Cell Exhaustion in an In Vitro Model by a SMARCA4/2 ATPase Inhibitor

SITC 2023 Poster 963: TME Immune-profiling of Ex Vivo Tumor Tissues and Their Functional Responses to Immuno-oncology Treatments

Poster

SITC 2023 Poster 963: TME Immune-profiling of Ex Vivo Tumor Tissues and Their Functional Responses to Immuno-oncology Treatments

SITC 2023 Poster 549: Multiomics Biomarker Analysis in 12 Mouse Syngeneic Models Under ICI Treatment

Poster

SITC 2023 Poster 549: Multiomics Biomarker Analysis in 12 Mouse Syngeneic Models Under ICI Treatment

SITC 2023 Poster 447: Evaluation of Efficacy and Toxicity of Human CD40 Agonists in C57BL/6-hCD40/hFcγRIIB HuGEMM™

Poster

SITC 2023 Poster 447: Evaluation of Efficacy and Toxicity of Human CD40 Agonists in C57BL/6-hCD40/hFcγRIIB HuGEMM™

SITC 2023 Poster 196: Tumor-associated SIRPα Expression Evaluation in Melanoma PDX Models via IHC for Potential ICI-predictive Applications

Poster

SITC 2023 Poster 196: Tumor-associated SIRPα Expression Evaluation in Melanoma PDX Models via IHC for Potential ICI-predictive Applications

SITC 2023 Poster 77: Analyzing Effects of Immunotherapies, such as Bispecific Antibodies and Cellular Therapy, Targeting EGFR Expression with a High...

Poster

SITC 2023 Poster 77: Analyzing Effects of Immunotherapies, such as Bispecific Antibodies and Cellular Therapy, Targeting EGFR Expression with a High...

ANE 2023 Poster LB_B16: Quantification of Immuno-oncology Drug Responses in Autologous Co-cultures of Ex Vivo Patient Tumor Tissues with PBMCs

Poster

ANE 2023 Poster LB_B16: Quantification of Immuno-oncology Drug Responses in Autologous Co-cultures of Ex Vivo Patient Tumor Tissues with PBMCs

ANE 2023 Poster C047: Comprehensive Curation of Label-free Proteomics Data for 186 Patient-Derived Xenograft (PDX) Models in HuBase™ Cancer Model Database

Poster

ANE 2023 Poster C047: Comprehensive Curation of Label-free Proteomics Data for 186 Patient-Derived Xenograft (PDX) Models in HuBase™ Cancer Model Database

ANE 2023 Poster C037: Large Scale Organoid Panel Drug Screening to Short-track Clinically-relevant Output

Poster

ANE 2023 Poster C037: Large Scale Organoid Panel Drug Screening to Short-track Clinically-relevant Output

ANE 2023 Poster C010: A Comprehensive Predictive Biomarker Analysis for MEK Inhibitor, Trametinib, in Patient-Derived Xenograft (PDX) Models

Poster

ANE 2023 Poster C010: A Comprehensive Predictive Biomarker Analysis for MEK Inhibitor, Trametinib, in Patient-Derived Xenograft (PDX) Models

ANE 2023 Poster A016: Novel LEF1 Gene Structural Variants in T Cell Acute Lymphoblastic Leukemia Patient-derived Xenograft Models

Poster

ANE 2023 Poster A016: Novel LEF1 Gene Structural Variants in T Cell Acute Lymphoblastic Leukemia Patient-derived Xenograft Models

ANE 2023 Poster A009: A New Version of Targeted Sequencing Panel (NGS-QC-PANEL) Enables Better Authentication and Characterization of Human and Mouse Samples

Poster

ANE 2023 Poster A009: A New Version of Targeted Sequencing Panel (NGS-QC-PANEL) Enables Better Authentication and Characterization of Human and Mouse Samples

ANE 2023 Poster A006: Characterizing Antitumor Response of PARP Inhibitors and Synergy of Docetaxel and PARP Inhibitors in BRCA1/2 Mutant TNBC Breast Cancer PDX Models

Poster

ANE 2023 Poster A006: Characterizing Antitumor Response of PARP Inhibitors and Synergy of Docetaxel and PARP Inhibitors in BRCA1/2 Mutant TNBC Breast Cancer PDX Models

What's Next in Preclinical Cancer Immunotherapy Research?

On-Demand Webinar

What's Next in Preclinical Cancer Immunotherapy Research?

Analyzing the Suppressive TME in in Vitro Based Assays

On-Demand Webinar

Analyzing the Suppressive TME in in Vitro Based Assays

Targeting T Cells Within the Cancer Immunity Cycle

On-Demand Webinar

Targeting T Cells Within the Cancer Immunity Cycle

Advanced In Vitro Technologies to Investigate Therapeutic Impact on the Cancer Immunity Cycle

On-Demand Webinar

Advanced In Vitro Technologies to Investigate Therapeutic Impact on the Cancer Immunity Cycle

Clinically Aligned Pretreated PDX Models

FactSheet

Clinically Aligned Pretreated PDX Models

CICON 2023 Poster 341: Prevention of Terminal T Cell Exhaustion Features by Treatment With Chromatin Remodeling Inhibitors

Poster

CICON 2023 Poster 341: Prevention of Terminal T Cell Exhaustion Features by Treatment With Chromatin Remodeling Inhibitors

Accelerate IO Drug Development with a Fast, Cost-effective, and Powerful Screening Tool

On-Demand Webinar

Accelerate IO Drug Development with a Fast, Cost-effective, and Powerful Screening Tool

Nanostring Spatial Multi-omics Services

FactSheet

Nanostring Spatial Multi-omics Services

Syngeneic Models

Quick Fact

Syngeneic Models

Data Science and Bioinformatics Services

FactSheet

Data Science and Bioinformatics Services

Establishment of Next Generation Pretreated PDX Models: A Tool for Precision Medicine

On-Demand Webinar

Establishment of Next Generation Pretreated PDX Models: A Tool for Precision Medicine

Integrated Preclinical Solutions to Guide Clinical Development of Bispecific Antibodies

On-Demand Webinar

Integrated Preclinical Solutions to Guide Clinical Development of Bispecific Antibodies

Navigating Cancer Model Databases for Optimized Model Selection

On-Demand Webinar

Navigating Cancer Model Databases for Optimized Model Selection

Advancing Proteomics Profiling in Tumor Xenograft Models: Overcoming Challenges and Accelerating Oncology Drug Discovery

On-Demand Webinar

Advancing Proteomics Profiling in Tumor Xenograft Models: Overcoming Challenges and Accelerating Oncology Drug Discovery

From Models to Patients: Harnessing Pretreated PDX Models for Precision Medicine

On-Demand Webinar

From Models to Patients: Harnessing Pretreated PDX Models for Precision Medicine

Functional Screening of Patient-Derived Organoids Using High-Content Imaging

On-Demand Webinar

Functional Screening of Patient-Derived Organoids Using High-Content Imaging

Decoding In Vitro Oncology Innovations: Organoids, OMICs, and Their Role in Early Drug Discovery and Clinical Applications

On-Demand Webinar

Decoding In Vitro Oncology Innovations: Organoids, OMICs, and Their Role in Early Drug Discovery and Clinical Applications

Microbiome Sequencing

FactSheet

Microbiome Sequencing

Pretreated PDX Models

FactSheet

Pretreated PDX Models

AAI 2023 Poster P892: An in vitro T Cell Dysfunction / Exhaustion Assay System to Non-clinically Assess T Cell-targeting Drug Efficacy

Poster

AAI 2023 Poster P892: An in vitro T Cell Dysfunction / Exhaustion Assay System to Non-clinically Assess T Cell-targeting Drug Efficacy

AACR 2023 Posters 6775: Indivumed Services - Combination of Spatial Transcriptomics and Multiplex IHC as Valuable Multi-Omics Tool for Biomarker Discovery

Poster

AACR 2023 Posters 6775: Indivumed Services - Combination of Spatial Transcriptomics and Multiplex IHC as Valuable Multi-Omics Tool for Biomarker Discovery

CRISPR/Cas9 Services for Cancer Disease Modeling

FactSheet

CRISPR/Cas9 Services for Cancer Disease Modeling

AACR 2023 Posters 29: Characterization of a Murine Intestinal Cancer Homograft Model for Therapeutic Evaluation

Poster

AACR 2023 Posters 29: Characterization of a Murine Intestinal Cancer Homograft Model for Therapeutic Evaluation

AACR 2023 Posters 52: Characterization of Murine Intrahepatic Cholangiocarcinoma Homograft Models for Therapeutic Evaluation

Poster

AACR 2023 Posters 52: Characterization of Murine Intrahepatic Cholangiocarcinoma Homograft Models for Therapeutic Evaluation

AACR 2023 Posters 185: Global Mapping of Pathway Modules and Phosphorylation Networks in PDX and Corresponding Organoid (PDXO) Models Treated with Targeted Therapies

Poster

AACR 2023 Posters 185: Global Mapping of Pathway Modules and Phosphorylation Networks in PDX and Corresponding Organoid (PDXO) Models Treated with Targeted Therapies

AACR 2023 Posters 198: Pan-cancer Assay-ready Organoid Drug Screening with Robust, Reproducible and Clinically-relevant Output

Poster

AACR 2023 Posters 198: Pan-cancer Assay-ready Organoid Drug Screening with Robust, Reproducible and Clinically-relevant Output

AACR 2023 Posters 401: Developing KRAS G12C Inhibitor-resistant Tumor Models for Efficacy Evaluation of Next-generation Anticancer Therapies

Poster

AACR 2023 Posters 401: Developing KRAS G12C Inhibitor-resistant Tumor Models for Efficacy Evaluation of Next-generation Anticancer Therapies

AACR 2023 Posters 497: HX301, a First-in-class ARK5i, Demonstrates Antitumor Activity in Preclinical HCC Models with High ARK5/Myc Expression

Poster

AACR 2023 Posters 497: HX301, a First-in-class ARK5i, Demonstrates Antitumor Activity in Preclinical HCC Models with High ARK5/Myc Expression

AACR 2023 Posters 579: Mini-tumors: Preclinical HCI Assays to Screen Anti-cancer Drugs in the Context of Organoids, Cancer-associated Fibroblasts and Immune Cells

Poster

AACR 2023 Posters 579: Mini-tumors: Preclinical HCI Assays to Screen Anti-cancer Drugs in the Context of Organoids, Cancer-associated Fibroblasts and Immune Cells

AACR 2023 Posters 2053: Structural Variants Detected by Optical Genome Mapping in Acute Lymphoblastic Leukemia Patient-Derived Xenograft Models

Poster

AACR 2023 Posters 2053: Structural Variants Detected by Optical Genome Mapping in Acute Lymphoblastic Leukemia Patient-Derived Xenograft Models

AACR 2023 Posters 2387: Characterization of Orthotopic Bioluminescent Patient-derived Xenografts Model of Glioma for Drug Discovery

Poster

AACR 2023 Posters 2387: Characterization of Orthotopic Bioluminescent Patient-derived Xenografts Model of Glioma for Drug Discovery

AACR 2023 Posters 2822: Maximizing Radiotherapy Impact: A Novel Preclinical Platform for Screening of Radiosensitizing Agents in Patient-derived Tumor Organoids

Poster

AACR 2023 Posters 2822: Maximizing Radiotherapy Impact: A Novel Preclinical Platform for Screening of Radiosensitizing Agents in Patient-derived Tumor Organoids

AACR 2023 Posters 2980: HX009, a First-in-class PD1xCD47 BsAb, Demonstrated Anti-AML Activity in PDX Models

Poster

AACR 2023 Posters 2980: HX009, a First-in-class PD1xCD47 BsAb, Demonstrated Anti-AML Activity in PDX Models

AACR 2023 Posters 4146: Unlocking IO Drug Potential by High Content Imaging of Immune Cell Co-cultures with Cancer Organoids from Diverse Cancer Indications

Poster

AACR 2023 Posters 4146: Unlocking IO Drug Potential by High Content Imaging of Immune Cell Co-cultures with Cancer Organoids from Diverse Cancer Indications

AACR 2023 Posters 4168: BALB/c-CD3EDG HuGEMM™ Mouse Model for Evaluation of CD3-targeted Tumor Immunotherapy

Poster

AACR 2023 Posters 4168: BALB/c-CD3EDG HuGEMM™ Mouse Model for Evaluation of CD3-targeted Tumor Immunotherapy

AACR 2023 Posters 4570: Expanding the 3D Ex Vivo Patient Tissue Platform Toolbox for Immuno-Oncology Drug Testing

Poster

AACR 2023 Posters 4570: Expanding the 3D Ex Vivo Patient Tissue Platform Toolbox for Immuno-Oncology Drug Testing

AACR 2023 Posters 4679: Molecular Pathology and BTKi Pharmacology of DLBCL PDX Models

Poster

AACR 2023 Posters 4679: Molecular Pathology and BTKi Pharmacology of DLBCL PDX Models

AACR 2023 Posters 5118: STING Agonist and TLR7/8 Agonist Overcome Anti-PD-1 Resistance Mediated by Loss of β2M

Poster

AACR 2023 Posters 5118: STING Agonist and TLR7/8 Agonist Overcome Anti-PD-1 Resistance Mediated by Loss of β2M

AACR 2023 Posters 6592: An AI Platform for Vascular and Fibrosis Analysis of Pathology Images

Poster

AACR 2023 Posters 6592: An AI Platform for Vascular and Fibrosis Analysis of Pathology Images

Matched Model Pairs and Patient-Derived Xenografts and Organoids Biobanks

On-Demand Webinar

Matched Model Pairs and Patient-Derived Xenografts and Organoids Biobanks

3D Ex vivo Patient Tissue Platform for Immuno-Oncology Drug Testing

Poster

3D Ex vivo Patient Tissue Platform for Immuno-Oncology Drug Testing

Next Generation Ion Mobility Mass Spectrometry-based Proteomics Services

FactSheet

Next Generation Ion Mobility Mass Spectrometry-based Proteomics Services

Preclinical biomarker discovery via in vivo and in vitro screening

On-Demand Webinar

Preclinical biomarker discovery via in vivo and in vitro screening

ENA 2022 Poster 013: Impact of Orthotopic Versus Subcutaneous Implantation on Patient-Derived Xenograft Transcriptome Profiles

Poster

ENA 2022 Poster 013: Impact of Orthotopic Versus Subcutaneous Implantation on Patient-Derived Xenograft Transcriptome Profiles

ENA 2022 Poster 051: HX301 (ON123300) Shows Broad Antitumor Activity in Preclinical Mantle Cell Lymphoma (MCL) Models, Inclusive of Those Resistant to BTKi

Poster

ENA 2022 Poster 051: HX301 (ON123300) Shows Broad Antitumor Activity in Preclinical Mantle Cell Lymphoma (MCL) Models, Inclusive of Those Resistant to BTKi

ENA 2022 Poster 121: Systematic Evaluation of Label-Free Protein Quantification Pipelines in 12 Mouse Syngeneic Models

Poster

ENA 2022 Poster 121: Systematic Evaluation of Label-Free Protein Quantification Pipelines in 12 Mouse Syngeneic Models

ENA 2022 Poster 122: Establishment of RET Inhibitor-Induced Resistant Patient-Derived Colorectal Cancer Xenograft Models

Poster

ENA 2022 Poster 122: Establishment of RET Inhibitor-Induced Resistant Patient-Derived Colorectal Cancer Xenograft Models

ENA 2022 Poster 266: Evaluating the Performance of Two NGS-Based Copy Number Aberration Detection Tools in Patient-Derived Organoids

Poster

ENA 2022 Poster 266: Evaluating the Performance of Two NGS-Based Copy Number Aberration Detection Tools in Patient-Derived Organoids

ENA 2022 Poster 273: Comparison of Biomarker Selection Method in High-Dimensional Genomic Data

Poster

ENA 2022 Poster 273: Comparison of Biomarker Selection Method in High-Dimensional Genomic Data

ENA 2022 Poster 321: High Content Screening of Ovarian Organoid Models to Accelerate Anti-Cancer Drug Discovery

Poster

ENA 2022 Poster 321: High Content Screening of Ovarian Organoid Models to Accelerate Anti-Cancer Drug Discovery

ENA 2022 Poster 324: Quantitative Analysis of EGFR Expression and Distribution Upon Drug Treatment in Colorectal Organoid Models

Poster

ENA 2022 Poster 324: Quantitative Analysis of EGFR Expression and Distribution Upon Drug Treatment in Colorectal Organoid Models

ENA 2022 Poster 332: Developing a Preclinical CD47 IHC Assay Using Patient-Like Samples for the Development...

Poster

ENA 2022 Poster 332: Developing a Preclinical CD47 IHC Assay Using Patient-Like Samples for the Development...

ENA 2022 Poster 343: HX301, a Novel CSF1Ri, Suppresses TAM and Enhances Tumor Immunity, Leading to Transit Tumor Response...

Poster

ENA 2022 Poster 343: HX301, a Novel CSF1Ri, Suppresses TAM and Enhances Tumor Immunity, Leading to Transit Tumor Response...

SITC 2022 Poster 040: NGS-Based Immunology Panel: Applications in Preclinical Immuno-Oncology Research

Poster

SITC 2022 Poster 040: NGS-Based Immunology Panel: Applications in Preclinical Immuno-Oncology Research

SITC 2022 Poster 069: A High Content Screening Platform for Testing Immunotherapies in Patient-Derived Organoids

Poster

SITC 2022 Poster 069: A High Content Screening Platform for Testing Immunotherapies in Patient-Derived Organoids

SITC 2022 Poster 106: A Preclinical Receptor Occupancy Assay for an Anti-PD-1 Monoclonal Antibody and an Anti-PD-1×CD47 Bispecific...

Poster

SITC 2022 Poster 106: A Preclinical Receptor Occupancy Assay for an Anti-PD-1 Monoclonal Antibody and an Anti-PD-1×CD47 Bispecific...

SITC 2022 Poster 199: 3D Ex vivo Patient Tissue Platform for Immuno-Oncology Drug Testing

Poster

SITC 2022 Poster 199: 3D Ex vivo Patient Tissue Platform for Immuno-Oncology Drug Testing

SITC 2022 Poster 491: HX009, A Novel BsAb Dual Targeting PD-1xCD47, Demonstrates Potent Anti-Lymphoma Activity

Poster

SITC 2022 Poster 491: HX009, A Novel BsAb Dual Targeting PD-1xCD47, Demonstrates Potent Anti-Lymphoma Activity

SITC 2022 Poster 950: TNFR2 HuGEMM™ Mouse Model for Evaluation of hTNFα-hTNFR2 Signaling Effect on iTreg Differentiation

Poster

SITC 2022 Poster 950: TNFR2 HuGEMM™ Mouse Model for Evaluation of hTNFα-hTNFR2 Signaling Effect on iTreg Differentiation

Preclinical Solutions for Drug Development Targeting Advanced Breast Cancer

On-Demand Webinar

Preclinical Solutions for Drug Development Targeting Advanced Breast Cancer

In Vivo Solutions for Oncology Drug Development

On-Demand Webinar

In Vivo Solutions for Oncology Drug Development

High-Throughput and High-Content Screening in Organoids and 3D Models

On-Demand Webinar

High-Throughput and High-Content Screening in Organoids and 3D Models

Lead Identification Screening Services in 3D

FactSheet

Lead Identification Screening Services in 3D

OmniScreen™ Large Scale Cancer Cell Line Screening Technology

FactSheet

OmniScreen™ Large Scale Cancer Cell Line Screening Technology

A New Dimension to Drug Discovery

eBook

A New Dimension to Drug Discovery

Patient-Derived Model Systems for Immuno-Oncology Drug Development

On-Demand Webinar

Patient-Derived Model Systems for Immuno-Oncology Drug Development

Immuno-Oncology Platforms

Quick Fact

Immuno-Oncology Platforms

Mouse I/O RNA-Seq Panel

Quick Fact

Mouse I/O RNA-Seq Panel

Genomics and High-Throughput Sequencing Capabilities

FactSheet

Genomics and High-Throughput Sequencing Capabilities

AACR22 Poster 615: Tim-3 as an Immune Therapy Target, Mechanism and Action, and Prognostic Values...

Poster

AACR22 Poster 615: Tim-3 as an Immune Therapy Target, Mechanism and Action, and Prognostic Values...

AACR22 Poster 615A: HuGEMM™ Modelling Toxicology of Species-Specific Immune Checkpoint Inhibitors

Poster

AACR22 Poster 615A: HuGEMM™ Modelling Toxicology of Species-Specific Immune Checkpoint Inhibitors

AACR22 Poster 617: MEK Inhibitor Rescued the Efficacy of PD-1 Blocker in STK11/LKB1 Mutated Colorectal Cancer Model

Poster

AACR22 Poster 617: MEK Inhibitor Rescued the Efficacy of PD-1 Blocker in STK11/LKB1 Mutated Colorectal Cancer Model

AACR22 Poster 1660: Comparison Between Surgical and Ultrasound-Guided Orthotopic Implantation of...

Poster

AACR22 Poster 1660: Comparison Between Surgical and Ultrasound-Guided Orthotopic Implantation of...

AACR22 Poster 2059: Immunotherapy Testing in 3D Ex Vivo Patient Tissue Platform with Preserved Tumor Microenvironment

Poster

AACR22 Poster 2059: Immunotherapy Testing in 3D Ex Vivo Patient Tissue Platform with Preserved Tumor Microenvironment

AACR22 Poster 2743: Tumor Growth Modeling and its Applications in Preclinical Pharmacology Studies to Improve...

Poster

AACR22 Poster 2743: Tumor Growth Modeling and its Applications in Preclinical Pharmacology Studies to Improve...

AACR22 Poster 3110: Identification of the Phosphorylation Network in PDX and Corresponding Organoid...

Poster

AACR22 Poster 3110: Identification of the Phosphorylation Network in PDX and Corresponding Organoid...

AACR22 Poster 3115: Establishment and Characterization of Patient-Derived Breast Cancer Models for Cancer Studies

Poster

AACR22 Poster 3115: Establishment and Characterization of Patient-Derived Breast Cancer Models for Cancer Studies

AACR22 Poster 3371: Impact of RNA Degradation on Transcriptomic Profiling in Tumor Samples from Syngeneic Mouse Models

Poster

AACR22 Poster 3371: Impact of RNA Degradation on Transcriptomic Profiling in Tumor Samples from Syngeneic Mouse Models

AACR22 Poster 3541: A Method to Visualize and Quantify Effects of Immunotherapies in a Physiologically Relevant 3D TME Model

Poster

AACR22 Poster 3541: A Method to Visualize and Quantify Effects of Immunotherapies in a Physiologically Relevant 3D TME Model

AACR22 Poster 4221: Characterization of OVA-Expressing Immunogenic Syngeneic Tumor Models for Immune Checkpoint Inhibitor Evaluation

Poster

AACR22 Poster 4221: Characterization of OVA-Expressing Immunogenic Syngeneic Tumor Models for Immune Checkpoint Inhibitor Evaluation

AACR22 Poster 4240: In Vivo Assessment of AICD and Cytokine Release Upon Treatment of OKT3 and CD3 Bispecific...

Poster

AACR22 Poster 4240: In Vivo Assessment of AICD and Cytokine Release Upon Treatment of OKT3 and CD3 Bispecific...

Biomarker, Bioanalysis and Bioinformatics Services

FactSheet

Biomarker, Bioanalysis and Bioinformatics Services

Diffuse Large B Cell Lymphoma PDX Models

FactSheet

Diffuse Large B Cell Lymphoma PDX Models

HCC827 NSCLC Cell Line Derived Xenograft Model

Application Note

HCC827 NSCLC Cell Line Derived Xenograft Model

Drug Discovery in 3D

Application Note

Drug Discovery in 3D

Biomarker Discovery for Immune Checkpoint Inhibitors

On-Demand Webinar

Biomarker Discovery for Immune Checkpoint Inhibitors

Proxy Study Director System

Quick Fact

Proxy Study Director System

Screening and Profiling The Added Value of High Content Imaging

Quick Fact

Screening and Profiling The Added Value of High Content Imaging

Elevate Your Insights into the Tumor Microenvironment

On-Demand Webinar

Elevate Your Insights into the Tumor Microenvironment

How to Accelerate Your Immuno-Oncology Studies with the Mouse I/O RNA-Seq Panel

On-Demand Webinar

How to Accelerate Your Immuno-Oncology Studies with the Mouse I/O RNA-Seq Panel

Image-Based Quantification of Myeloid Cell Repolarization and their Interplay within the Tumor Microenvironment in 3D

On-Demand Webinar

Image-Based Quantification of Myeloid Cell Repolarization and their Interplay within the Tumor Microenvironment in 3D

Advancing Authentication: Next-Generation Technology for Cell Line and Model Authentication

On-Demand Webinar

Advancing Authentication: Next-Generation Technology for Cell Line and Model Authentication

Clinically Relevant Cell-Based Solutions for Target Identification

On-Demand Webinar

Clinically Relevant Cell-Based Solutions for Target Identification

A BiTE-Sized Discussion on Next-Generation Preclinical Models

On-Demand Webinar

A BiTE-Sized Discussion on Next-Generation Preclinical Models

Patient-Derived Organoid and Immune Cell Co-Cultures for Immunotherapy Development

On-Demand Webinar

Patient-Derived Organoid and Immune Cell Co-Cultures for Immunotherapy Development

Leveraging 3D In Vitro Models for Oncology Drug Discovery

On-Demand Webinar

Leveraging 3D In Vitro Models for Oncology Drug Discovery

Demonstrating Clinical Relevance in 3D In Vitro Modeling with HUB Organoids

On-Demand Webinar

Demonstrating Clinical Relevance in 3D In Vitro Modeling with HUB Organoids

Assessing Immunotherapy Toxicity in NHPs

On-Demand Webinar

Assessing Immunotherapy Toxicity in NHPs

Efficacy and irAE Assessment Of Therapeutic Antibodies With Target Specific Knock-In Models

On-Demand Webinar

Efficacy and irAE Assessment Of Therapeutic Antibodies With Target Specific Knock-In Models

Shifting the Paradigm of Cancer Treatment: How Can Optical Imaging Help?

On-Demand Webinar

Shifting the Paradigm of Cancer Treatment: How Can Optical Imaging Help?

Next Generation Syngeneic Models to Facilitate Immuno-Oncology Research

On-Demand Webinar

Next Generation Syngeneic Models to Facilitate Immuno-Oncology Research

Are You Choosing the Right Model? A Guide to Selecting Your Next Immuno-Oncology Model

On-Demand Webinar

Are You Choosing the Right Model? A Guide to Selecting Your Next Immuno-Oncology Model

How to Leverage Tumor Models for Pancreatic Cancer Research

On-Demand Webinar

How to Leverage Tumor Models for Pancreatic Cancer Research

Patient-Derived Xenografts as Models for Metastatic Breast Cancer and Preclinical Therapy Testing

On-Demand Webinar

Patient-Derived Xenografts as Models for Metastatic Breast Cancer and Preclinical Therapy Testing

How to Detect, Characterize, and Evaluate CAR-T Cell Therapies

On-Demand Webinar

How to Detect, Characterize, and Evaluate CAR-T Cell Therapies

The Ultimate Guide to Mouse Clinical Trials

On-Demand Webinar

The Ultimate Guide to Mouse Clinical Trials

Patient-Derived Xenografts: New Advancements in Preclinical Prostate Cancer Models

On-Demand Webinar

Patient-Derived Xenografts: New Advancements in Preclinical Prostate Cancer Models

Applications of HUB Tumor Organoids in Oncology Drug Discovery

On-Demand Webinar

Applications of HUB Tumor Organoids in Oncology Drug Discovery

In Silico Applications for In Vitro Drug Discovery

On-Demand Webinar

In Silico Applications for In Vitro Drug Discovery

Tumor Organoids: A Paradigm Shift in Oncology Drug Discovery

On-Demand Webinar

Tumor Organoids: A Paradigm Shift in Oncology Drug Discovery

3D In Vitro Drug Discovery: When and How to Use Tumor Organoids

On-Demand Webinar

3D In Vitro Drug Discovery: When and How to Use Tumor Organoids

Preclinical Prostate Cancer Models: Which One is Right For You?

On-Demand Webinar

Preclinical Prostate Cancer Models: Which One is Right For You?

Exploring Translational Capabilities of Preclinical IBD Models

On-Demand Webinar

Exploring Translational Capabilities of Preclinical IBD Models

Imaging Orthotopic and Metastatic Preclinical Models for Oncology Drug Discovery

On-Demand Webinar

Imaging Orthotopic and Metastatic Preclinical Models for Oncology Drug Discovery

Microbiome Drug Development with Whole Communities and Defined Consortia

On-Demand Webinar

Microbiome Drug Development with Whole Communities and Defined Consortia

Beyond Syngeneics – Novel Tools for Addressing Human Specificity in Immuno-Oncology

On-Demand Webinar

Beyond Syngeneics – Novel Tools for Addressing Human Specificity in Immuno-Oncology

Murine Immuno-Oncology Models: A Head-to-Head Comparison Between Syngeneics and Tumor Homografts

On-Demand Webinar

Murine Immuno-Oncology Models: A Head-to-Head Comparison Between Syngeneics and Tumor Homografts

Mouse Clinical Trials: The Power Behind Study Design

On-Demand Webinar

Mouse Clinical Trials: The Power Behind Study Design

Interrogating Syngeneic Models in Large Scale, How to Use Immunoprofiling Data to Improve your Studies

On-Demand Webinar

Interrogating Syngeneic Models in Large Scale, How to Use Immunoprofiling Data to Improve your Studies

In Vitro and Ex Vivo Assays to Accelerate Immuno-Oncology Drug Discovery

On-Demand Webinar

In Vitro and Ex Vivo Assays to Accelerate Immuno-Oncology Drug Discovery

Immuno-Oncology: 3 Strategies for Applying Humanized Models

On-Demand Webinar

Immuno-Oncology: 3 Strategies for Applying Humanized Models

Exploring Translational Capabilities of PDX Models across In Vivo, In Vitro and Ex Vivo Applications

On-Demand Webinar

Exploring Translational Capabilities of PDX Models across In Vivo, In Vitro and Ex Vivo Applications

Vascular and Neural Complications in Rodent Models of Obesity and Type 2 Diabetes

On-Demand Webinar

Vascular and Neural Complications in Rodent Models of Obesity and Type 2 Diabetes

Translational Platforms to Model Pre-Diabetes, Diabetes, and Diabetic Complications

On-Demand Webinar

Translational Platforms to Model Pre-Diabetes, Diabetes, and Diabetic Complications

3 Strategies to Identify Clinically Predictive Biomarkers in the Preclinical Space

On-Demand Webinar

3 Strategies to Identify Clinically Predictive Biomarkers in the Preclinical Space

3D Ex Vivo Patient Tissue Platform

FactSheet

3D Ex Vivo Patient Tissue Platform

ENA21 Poster 115: 3D Ex Vivo Patient Tissue Platform for Oncology Drug Evaluation

Poster

ENA21 Poster 115: 3D Ex Vivo Patient Tissue Platform for Oncology Drug Evaluation

ENA21 Poster 158: Phenotypic Analysis of Myeloid Cells in a 3D Image-Based...

Poster

ENA21 Poster 158: Phenotypic Analysis of Myeloid Cells in a 3D Image-Based...

ENA21 Poster 113: Image-Based Quantification of Immunotherapeutic Effect on the Tumor-Immune...

Poster

ENA21 Poster 113: Image-Based Quantification of Immunotherapeutic Effect on the Tumor-Immune...

ENA21 Poster 003: In vitro and In vivo Characterization of CCR8 Humanized Mouse Model (HuGEMM™)

Poster

ENA21 Poster 003: In vitro and In vivo Characterization of CCR8 Humanized Mouse Model (HuGEMM™)

ENA21 Poster 103: Introduction of a Single Strain of Bacillus into a Germ-Free Environment...

Poster

ENA21 Poster 103: Introduction of a Single Strain of Bacillus into a Germ-Free Environment...

ENA21 Poster 005: Establishment and Characterization of a Panel of Advanced...

Poster

ENA21 Poster 005: Establishment and Characterization of a Panel of Advanced...

AACR21 Poster 502: In Vitro Characterization of Antibodies Targeting the SIRPa–CD47 Phagocytosis

Poster

AACR21 Poster 502: In Vitro Characterization of Antibodies Targeting the SIRPa–CD47 Phagocytosis

SITC20 Poster 647: Humanized CD137 Knock-In Mouse Model to Assess Chimeric Urelumab

Poster

SITC20 Poster 647: Humanized CD137 Knock-In Mouse Model to Assess Chimeric Urelumab

SITC20 Poster 527: Advance Immunotherapy Development with a Tumor Organoid/Immune Cell Co-Culture System

Poster

SITC20 Poster 527: Advance Immunotherapy Development with a Tumor Organoid/Immune Cell Co-Culture System

SITC20 Poster 245: New hTLR8 Knock-In Mouse Model for Enhanced Immunotherapy Studies

Poster

SITC20 Poster 245: New hTLR8 Knock-In Mouse Model for Enhanced Immunotherapy Studies

AACR20 Poster 2788: Orthotopic, Bioluminescent Syngeneic Models for I/O Evaluation

Poster

AACR20 Poster 2788: Orthotopic, Bioluminescent Syngeneic Models for I/O Evaluation

AACR20 Poster 2798: Profiling the Cancer Stem Cell Components of PDX and PDX-Derived Organoids

Poster

AACR20 Poster 2798: Profiling the Cancer Stem Cell Components of PDX and PDX-Derived Organoids

AACR20 Poster 5615: Assess Human Specific Anti-CD47 Antibodies with hCD47/hSIPRα Double Knock-In Mice

Poster

AACR20 Poster 5615: Assess Human Specific Anti-CD47 Antibodies with hCD47/hSIPRα Double Knock-In Mice

AACR20 Poster 5616: Evaluate Immunotherapy Mechanism of Action with Immune Cell Lineage Specific DTR Models

Poster

AACR20 Poster 5616: Evaluate Immunotherapy Mechanism of Action with Immune Cell Lineage Specific DTR Models

SITC20 Poster 237: In Vitro Potency Assays to Assess Next Generation Checkpoint Inhibitors

Poster

SITC20 Poster 237: In Vitro Potency Assays to Assess Next Generation Checkpoint Inhibitors

AACR20 Poster 5963: Characterizing Preclinical Murine I/O Model Tumor-Immune Interactions

Poster

AACR20 Poster 5963: Characterizing Preclinical Murine I/O Model Tumor-Immune Interactions

AACR-NCI-EORTC 19 Poster C118: Implantation Site Effects on PDX

Poster

AACR-NCI-EORTC 19 Poster C118: Implantation Site Effects on PDX

ENA20 Poster 207: Benchmarking Syngeneic Tumor Immunity through Immune Subset Depletion

Poster

ENA20 Poster 207: Benchmarking Syngeneic Tumor Immunity through Immune Subset Depletion

AACR-NCI-EORTC 19 Poster A009: Imaging Systemic Hematologic Xenografts

Poster

AACR-NCI-EORTC 19 Poster A009: Imaging Systemic Hematologic Xenografts

ENA20 Poster 29: New Human GITR Knock-In Model for Preclinical Efficacy Studies

Poster

ENA20 Poster 29: New Human GITR Knock-In Model for Preclinical Efficacy Studies

AACR20 Poster 2768: New Bioluminescent Orthotopic KPC Murine Homograft Model for PDAC Drug Development

Poster

AACR20 Poster 2768: New Bioluminescent Orthotopic KPC Murine Homograft Model for PDAC Drug Development

AACR-NCI-EORTC 19 Poster A025: Correlating PDX Genomic and Proteomic Profiles

Poster

AACR-NCI-EORTC 19 Poster A025: Correlating PDX Genomic and Proteomic Profiles

AACR-NCI-EORTC 19 Poster C102: Understanding Anti-PD-1 MOA Through Immune Cell Depletion

Poster

AACR-NCI-EORTC 19 Poster C102: Understanding Anti-PD-1 MOA Through Immune Cell Depletion

AACR-NCI-EORTC 19 Poster A026: Developing an Automated Biomarker Discovery Platform

Poster

AACR-NCI-EORTC 19 Poster A026: Developing an Automated Biomarker Discovery Platform

AACR-NCI-EORTC 19 Poster A010: Enhancing Syngeneic Immunogenicity through OVA Expression

Poster

AACR-NCI-EORTC 19 Poster A010: Enhancing Syngeneic Immunogenicity through OVA Expression

AACR-NCI-EORTC 19 Poster B041: Imaging Orthotopic Syngeneic Models

Poster

AACR-NCI-EORTC 19 Poster B041: Imaging Orthotopic Syngeneic Models

AACR19 Poster 5111: New Web Platform for Preclinical Data Analysis

Poster

AACR19 Poster 5111: New Web Platform for Preclinical Data Analysis

AACR19 Poster 4613: Evaluating Mathematical Models of Tumor Growth Kinetics

Poster

AACR19 Poster 4613: Evaluating Mathematical Models of Tumor Growth Kinetics

AACR19 Poster 4610: Predictive Biomarker Discovery in CRC using PDX Models

Poster

AACR19 Poster 4610: Predictive Biomarker Discovery in CRC using PDX Models

AACR19 Poster 4609: Varied Panel of Sarcoma PDX Models Developed

Poster

AACR19 Poster 4609: Varied Panel of Sarcoma PDX Models Developed

AACR19 Poster 4124: Optimizing a Functional ICB Screening Assay System

Poster

AACR19 Poster 4124: Optimizing a Functional ICB Screening Assay System

AACR19 Poster 3418: Authenticating Tumor Models with an NGS-Based SNP Array

Poster

AACR19 Poster 3418: Authenticating Tumor Models with an NGS-Based SNP Array

AACR19 Poster 1925: New PDX-Derived Cancer Organoids Developed

Poster

AACR19 Poster 1925: New PDX-Derived Cancer Organoids Developed

AACR19 Poster 1503: Immune Cell Depletion Affects aPD-1 Efficacy

Poster

AACR19 Poster 1503: Immune Cell Depletion Affects aPD-1 Efficacy

AACR19 Poster 1060: Prostate Cancer PDX for Predictive Preclinical Studies

Poster

AACR19 Poster 1060: Prostate Cancer PDX for Predictive Preclinical Studies

AACR19 Poster 87: Bioluminescent Imaging of Orthotopic Syngeneic Models

Poster

AACR19 Poster 87: Bioluminescent Imaging of Orthotopic Syngeneic Models

Using PDX for In Vivo CAR-T Cell Therapy Assessment

Poster

Using PDX for In Vivo CAR-T Cell Therapy Assessment

ENA18 Poster 329: Orthotopic Syngeneics: More Clinically Relevant I/O Models

Poster

ENA18 Poster 329: Orthotopic Syngeneics: More Clinically Relevant I/O Models

ENA18 Poster 327: Prostate Cancer Patient-Derived Xenograft Treatment Data

Poster

ENA18 Poster 327: Prostate Cancer Patient-Derived Xenograft Treatment Data

ENA18 Poster 313: Orthotopic Homograft Tumours Display Distinct TIL Patterns

Poster

ENA18 Poster 313: Orthotopic Homograft Tumours Display Distinct TIL Patterns

ENA18 Poster 312: Comparing Kidney Cancer Genomics Across Populations

Poster

ENA18 Poster 312: Comparing Kidney Cancer Genomics Across Populations

ENA18 Poster 305: Comparing Categorical Response Methods for Tumour Model Studies

Poster

ENA18 Poster 305: Comparing Categorical Response Methods for Tumour Model Studies

ENA18 Poster 250: Tumour Homografts for Prostate Cancer I/O Development

Poster

ENA18 Poster 250: Tumour Homografts for Prostate Cancer I/O Development

ENA18 Poster 241: Characterising Syngeneics to Guide Model Selection

Poster

ENA18 Poster 241: Characterising Syngeneics to Guide Model Selection

ENA18 Poster 240: Evaluate Bispecific Antibodies with PBMC-Humanised Models

Poster

ENA18 Poster 240: Evaluate Bispecific Antibodies with PBMC-Humanised Models

ENA18 Poster 226: Immune Checkpoint Double Knock-In Models for I/O Testing

Poster

ENA18 Poster 226: Immune Checkpoint Double Knock-In Models for I/O Testing

ECI18 Poster: Assess Targeted I/O Agents with PBMC-Humanized Models

Poster

ECI18 Poster: Assess Targeted I/O Agents with PBMC-Humanized Models

996: Novel PDAC Murine Homografts for I/O Drug Development

Poster

996: Novel PDAC Murine Homografts for I/O Drug Development

AIS18 Poster: Bispecific Antibody Evaluation via CD3E Transgenic Model

Poster

AIS18 Poster: Bispecific Antibody Evaluation via CD3E Transgenic Model

CIMT18 Abstract 60: In Vitro Assay Platform to Test Anti-CD47 Agents

Poster

CIMT18 Abstract 60: In Vitro Assay Platform to Test Anti-CD47 Agents

CIMT18 Abstract 230: Improved CD3E Transgenic Mouse Model for I/O Agent Testing

Poster

CIMT18 Abstract 230: Improved CD3E Transgenic Mouse Model for I/O Agent Testing

AACR18 Poster 1016: Investigating the TME through PDX RNAseq Analysis

Poster

AACR18 Poster 1016: Investigating the TME through PDX RNAseq Analysis

AACR18 Poster 1051: WES and RNAseq Comparison of PDX Mutations

Poster

AACR18 Poster 1051: WES and RNAseq Comparison of PDX Mutations

AACR18 Poster 1144: KPC Homograft Models for PDAC Combination I/O Studies

Poster

AACR18 Poster 1144: KPC Homograft Models for PDAC Combination I/O Studies

AACR18 Poster 2167: DLBCL PDX Models with Diverse Genotypes for BTKi Testing

Poster

AACR18 Poster 2167: DLBCL PDX Models with Diverse Genotypes for BTKi Testing

AACR18 Poster 3809: IDO1 Inhibition Assay Measuring Kyn Levels Developed

Poster

AACR18 Poster 3809: IDO1 Inhibition Assay Measuring Kyn Levels Developed

AACR18 Poster 4556: Disrupting the CD47-SIRPa Anti-Phagocytic Axis in I/O

Poster

AACR18 Poster 4556: Disrupting the CD47-SIRPa Anti-Phagocytic Axis in I/O

AACR18 Poster 5033: Recapitulating the TME in Ex Vivo 3D Tumor Growth Assay

Poster

AACR18 Poster 5033: Recapitulating the TME in Ex Vivo 3D Tumor Growth Assay

AACR18 Poster 5669: CD3E Transgenic Mouse Model for Bispecific Antibody Testing

Poster

AACR18 Poster 5669: CD3E Transgenic Mouse Model for Bispecific Antibody Testing

AACR18 Poster 5677: PBMC-Humanized Models for Targeted Cancer Immunotherapy

Poster

AACR18 Poster 5677: PBMC-Humanized Models for Targeted Cancer Immunotherapy

P01.03: KPC Homograft Models for PDAC Combination Immunotherapy Development

Poster

P01.03: KPC Homograft Models for PDAC Combination Immunotherapy Development

Humanized OX40 Mouse Models for Preclinical I/O Studies

Poster

Humanized OX40 Mouse Models for Preclinical I/O Studies

PBMC-Humanized Models for In Vivo I/O Studies

Poster

PBMC-Humanized Models for In Vivo I/O Studies

TM London17: Orthotopic, Bioluminescent Syngeneic HCC Models for Immunotherapy Assessment

Poster

TM London17: Orthotopic, Bioluminescent Syngeneic HCC Models for Immunotherapy Assessment

NGCS17: Orthotopic, Bioluminescent Ovarian Cancer Xenograft Models Developed

Poster

NGCS17: Orthotopic, Bioluminescent Ovarian Cancer Xenograft Models Developed

AACR17 New Horizon A27: Immunosuppressive Phenotype and Poor I/O Agent Response Correlation

Poster

AACR17 New Horizon A27: Immunosuppressive Phenotype and Poor I/O Agent Response Correlation

AACR17 New Horizon B21: Evaluate and Quantify Two-Drug Combination Effects In Vitro

Poster

AACR17 New Horizon B21: Evaluate and Quantify Two-Drug Combination Effects In Vitro

AACR17 New Horizon B59: Clinically Relevant DLBCL PDX Models for BTK Inhibitor Testing

Poster

AACR17 New Horizon B59: Clinically Relevant DLBCL PDX Models for BTK Inhibitor Testing

AACR17 New Horizon B74: Characterization of PBMC Humanized Models for I/O Studies

Poster

AACR17 New Horizon B74: Characterization of PBMC Humanized Models for I/O Studies

AACR17 New Horizon B75: Comprehensive Profiling of a Variety of I/O Models

Poster

AACR17 New Horizon B75: Comprehensive Profiling of a Variety of I/O Models

AACR17 New Horizon B78: Disrupting the CD47-SIRPa Anti-Phagocytic Axis: A Novel I/O Approach

Poster

AACR17 New Horizon B78: Disrupting the CD47-SIRPa Anti-Phagocytic Axis: A Novel I/O Approach

AACR17 New Horizon B80: Combination Screening of I/O and Targeted Agents In Vitro

Poster

AACR17 New Horizon B80: Combination Screening of I/O and Targeted Agents In Vitro

EORTC17 A003: Immunocompetent AML Model for Preclinical Efficacy Testing

Poster

EORTC17 A003: Immunocompetent AML Model for Preclinical Efficacy Testing

EORTC17 A010: Orthotopic, Bioluminescent Syngeneic HCC Models Developed

Poster

EORTC17 A010: Orthotopic, Bioluminescent Syngeneic HCC Models Developed

EORTC17 A026: Cetuximab Response vs EGFR Expression Analysis

Poster

EORTC17 A026: Cetuximab Response vs EGFR Expression Analysis

EORTC17 A203: Evaluate Human-Specific TIM-3 Immunotherapeutics In Vivo

Poster

EORTC17 A203: Evaluate Human-Specific TIM-3 Immunotherapeutics In Vivo

EORTC17 A207: Evaluate the Efficacy of Human OX40 Therapeutics and Combination Regimens In Vivo

Poster

EORTC17 A207: Evaluate the Efficacy of Human OX40 Therapeutics and Combination Regimens In Vivo

EORTC17 B002: Developing Novel Immuno-Oncology Assays for Anti-CD47 Research

Poster

EORTC17 B002: Developing Novel Immuno-Oncology Assays for Anti-CD47 Research

EORTC17 B014: Cost Effective, In Vivo Syngeneic I/O Agent Screening Panel

Poster

EORTC17 B014: Cost Effective, In Vivo Syngeneic I/O Agent Screening Panel

EORTC17 B209: PDX as Surrogate Models for TME Investigation

Poster

EORTC17 B209: PDX as Surrogate Models for TME Investigation

Targeting CD47: A Novel Immunotherapy Approach Against Cancer

Poster

Targeting CD47: A Novel Immunotherapy Approach Against Cancer

MiXeno™ – Simple, Fast, and Cost-Effective Humanized Models

Poster

MiXeno™ – Simple, Fast, and Cost-Effective Humanized Models

Humanized CD137 Models for Preclinical Drug Development

Poster

Humanized CD137 Models for Preclinical Drug Development

AACR17 Poster 1647: MiXeno™ - a Rapid and Simple Strategy for Model Humanization

Poster

AACR17 Poster 1647: MiXeno™ - a Rapid and Simple Strategy for Model Humanization

AACR17 Poster 1658: CD137 Target Humanized Model Established

Poster

AACR17 Poster 1658: CD137 Target Humanized Model Established

AACR17 Poster 2696: Anti-PD-1 Induced Microbiota Changes

Poster

AACR17 Poster 2696: Anti-PD-1 Induced Microbiota Changes

AACR17 Poster 2811: Evaluate TILs and TAMs in Syngeneic Models

Poster

AACR17 Poster 2811: Evaluate TILs and TAMs in Syngeneic Models

AACR17 Poster 2824: Discover New PDX Models for Prostate Cancer

Poster

AACR17 Poster 2824: Discover New PDX Models for Prostate Cancer

AACR17 Poster 5597: In Vitro Combination Screening of IO and Targeted Agents

Poster

AACR17 Poster 5597: In Vitro Combination Screening of IO and Targeted Agents

Immunology Syngeneic Models Demonstrate Additive Effects of Combination

Poster

Immunology Syngeneic Models Demonstrate Additive Effects of Combination

Development of a Humanized Mouse Model for Direct Evaluation of Anti-Human PD-L1 Antibodies

Poster

Development of a Humanized Mouse Model for Direct Evaluation of Anti-Human PD-L1 Antibodies

A Panel of Well-Characterized Syngeneic Models for MuScreen™ In Vivo Screening

Poster

A Panel of Well-Characterized Syngeneic Models for MuScreen™ In Vivo Screening

Autocrine c-Met/HGF HCC PDX: Evaluation of a Biologic Targeting c-Met

Poster

Autocrine c-Met/HGF HCC PDX: Evaluation of a Biologic Targeting c-Met

Immunization is Critical to PD-1/PD- L1 Response in a Mouse Breast Cancer

Poster

Immunization is Critical to PD-1/PD- L1 Response in a Mouse Breast Cancer

Orthotopic Syngeneic Tumor Models for Preclinical Evaluation of Cancer

Poster

Orthotopic Syngeneic Tumor Models for Preclinical Evaluation of Cancer

RNAseq and FACS Profiling of Syngeneic Mouse Models Treated with Immune

Poster

RNAseq and FACS Profiling of Syngeneic Mouse Models Treated with Immune

A HuGEMM h/mPD1 Mouse Model for Testing Anti-Human PD-1 Therapeutics

Poster

A HuGEMM h/mPD1 Mouse Model for Testing Anti-Human PD-1 Therapeutics

Application of Image-Guided Irradiation to a Preclinical Bioluminescent

Poster

Application of Image-Guided Irradiation to a Preclinical Bioluminescent

Application of Small Animal Image-Guided Irradiation to Preclinical In Vivo

Poster

Application of Small Animal Image-Guided Irradiation to Preclinical In Vivo

Building a Comprehensive and Fully Annotated Patient Tumor Derived Xenograft

Poster

Building a Comprehensive and Fully Annotated Patient Tumor Derived Xenograft

Building Mouse Tumor Derived Allografts for Immuno-Oncology Research

Poster

Building Mouse Tumor Derived Allografts for Immuno-Oncology Research

Cell-based Screening Identifies Gene Expression Signature Correlated with

Poster

Cell-based Screening Identifies Gene Expression Signature Correlated with

Drug Resistant Murine Tumor Models Facilitate Development of Next Generation Anticancer Therapeutics

Poster

Drug Resistant Murine Tumor Models Facilitate Development of Next Generation Anticancer Therapeutics

Drug Resistant Murine Tumor Models Facilitate Development of Next Generation

Poster

Drug Resistant Murine Tumor Models Facilitate Development of Next Generation

Establishment of a Humanized PD-1 Mouse Model for In Vivo Pharmacological

Poster

Establishment of a Humanized PD-1 Mouse Model for In Vivo Pharmacological

Evaluate In Vivo Efficacy of Antitumor Immunotherapeutics Using MiXeno™ Mouse

Poster

Evaluate In Vivo Efficacy of Antitumor Immunotherapeutics Using MiXeno™ Mouse

Immunological Characterization: Allograft of Primary Murine Breast Cancer

Poster

Immunological Characterization: Allograft of Primary Murine Breast Cancer

In Vivo and In Vitro Generation and Characterisation of EGFR-TKI Resistance in

Poster

In Vivo and In Vitro Generation and Characterisation of EGFR-TKI Resistance in

Induction of Resistance to Targeted Therapies in Patient-Derived Xenograft Models

Poster

Induction of Resistance to Targeted Therapies in Patient-Derived Xenograft Models

Overcoming Acquired Resistance in NSCLC with Targeted Beam Irradiation in

Poster

Overcoming Acquired Resistance in NSCLC with Targeted Beam Irradiation in

Patient-Derived AML Xenografts for Drug Evaluation

Poster

Patient-Derived AML Xenografts for Drug Evaluation

Patient-Derived Xenograft Seem to Have Closer Global Expression Profile to that

Poster

Patient-Derived Xenograft Seem to Have Closer Global Expression Profile to that

Patient Relevant Preclinical In Vivo Models Using Image-Guided Small Animal

Poster

Patient Relevant Preclinical In Vivo Models Using Image-Guided Small Animal

Profiling of Syngeneic Models by Anti-PD-1, PD-L1 and CTLA-4 Immunotherapeutics

Poster

Profiling of Syngeneic Models by Anti-PD-1, PD-L1 and CTLA-4 Immunotherapeutics

Profiling of Syngeneic Models by Check Point Inhibitors, RNAseq, and FACS

Poster

Profiling of Syngeneic Models by Check Point Inhibitors, RNAseq, and FACS

Response to Checkpoint Inhibition by GEMM Breast Cancer Allograft

Poster

Response to Checkpoint Inhibition by GEMM Breast Cancer Allograft

Syngeneic Models for Developing Cancer Therapeutics Targeting Immune System

Poster

Syngeneic Models for Developing Cancer Therapeutics Targeting Immune System

Treatment of Patient-Derived NSCLC Xenograft Preclinical Models Using

Poster

Treatment of Patient-Derived NSCLC Xenograft Preclinical Models Using

Validation of Anti-Human PD-1 and PD-L1 Antibodies in MiXeno™ Mouse Models

Poster

Validation of Anti-Human PD-1 and PD-L1 Antibodies in MiXeno™ Mouse Models

X-MAN™ Isogenic DualXeno™ Models with KRAS Mutation Predicts the Effect of

Poster

X-MAN™ Isogenic DualXeno™ Models with KRAS Mutation Predicts the Effect of

Myeloid Cell Repolarization HCI Assay

FactSheet

Myeloid Cell Repolarization HCI Assay

OrganoidBase™

Quick Fact

OrganoidBase™

3D In Vitro HCI for Immuno-Oncology

FactSheet

3D In Vitro HCI for Immuno-Oncology

Cell Line Authentication with Deep Sequencing

FactSheet

Cell Line Authentication with Deep Sequencing

MuBase®

Quick Fact

MuBase®

Tumor Organoid Immuno-Oncology Applications

Quick Fact

Tumor Organoid Immuno-Oncology Applications

Organoids for Preclinical Oncology Drug Development and Validation

FactSheet

Organoids for Preclinical Oncology Drug Development and Validation

When and How to Use Tumor Organoids in Drug Discovery

White Paper

When and How to Use Tumor Organoids in Drug Discovery

Genomics Services

Quick Fact

Genomics Services

3 Preclinical Strategies to Identify Predictive Cancer Biomarkers

White Paper

3 Preclinical Strategies to Identify Predictive Cancer Biomarkers

How to Detect, Characterize, and Evaluate CAR-T Cell Therapies

White Paper

How to Detect, Characterize, and Evaluate CAR-T Cell Therapies

Rare Cell Analysis

Quick Fact

Rare Cell Analysis

Disrupting the Oncology Drug Development Workflow with PDXO Models

White Paper

Disrupting the Oncology Drug Development Workflow with PDXO Models

Advanced Statistical Analyses to Optimize MCTs

White Paper

Advanced Statistical Analyses to Optimize MCTs

Bioinformatics

Quick Fact

Bioinformatics

Biomarker Discovery

Quick Fact

Biomarker Discovery

Cytokine and Chemokine Profiling

Quick Fact

Cytokine and Chemokine Profiling

Histology and Digital Pathology

Quick Fact

Histology and Digital Pathology

Biomarker Services

Quick Fact

Biomarker Services

Advantages in 3D In Vitro Modeling with HUB Organoids

White Paper

Advantages in 3D In Vitro Modeling with HUB Organoids

Imaging Orthotopic and Metastatic Preclinical Tumor Models

White Paper

Imaging Orthotopic and Metastatic Preclinical Tumor Models

Advanced Models and Novel I/O Technologies for Preclinical PDAC Research

White Paper

Advanced Models and Novel I/O Technologies for Preclinical PDAC Research

Optimizing Syngeneic Translatability through POC and Target Engagement Studies

White Paper

Optimizing Syngeneic Translatability through POC and Target Engagement Studies

MuScreen

Quick Fact

MuScreen

MuPrime Tumor Homografts

Quick Fact

MuPrime Tumor Homografts

HuGEMM and HuCELL

Quick Fact

HuGEMM and HuCELL

New Advancements in Preclinical Prostate Cancer PDX Models

White Paper

New Advancements in Preclinical Prostate Cancer PDX Models

DMPK Services

Quick Fact

DMPK Services

Immunocompetent Murine Models: A Guide to Understanding their Place in Immuno-Oncology Drug Discovery

White Paper

Immunocompetent Murine Models: A Guide to Understanding their Place in Immuno-Oncology Drug Discovery

3D Cell Culture Platform In Vitro/Ex Vivo Assays for Cancer Pharmacology

FactSheet

3D Cell Culture Platform In Vitro/Ex Vivo Assays for Cancer Pharmacology

CAR-T Therapy

FactSheet

CAR-T Therapy

HuGEMM™ and HuCELL™ Models

FactSheet

HuGEMM™ and HuCELL™ Models

FGFR3 Fusion In Vivo Xenograft Platform

FactSheet

FGFR3 Fusion In Vivo Xenograft Platform

MuPrime™ Model

FactSheet

MuPrime™ Model

HuKemia®

FactSheet

HuKemia®

HuPrime®

FactSheet

HuPrime®

MuScreen™

FactSheet

MuScreen™

MiXeno™

FactSheet

MiXeno™

Syngeneic Models

FactSheet

Syngeneic Models

HuTrial™ Case Studies

Application Note

HuTrial™ Case Studies

HuTrial™

Quick Fact

HuTrial™

HuSignature™

Quick Fact

HuSignature™

CrownSyn™

Quick Fact

CrownSyn™

HuMark™

Quick Fact

HuMark™

HuBase™

Quick Fact

HuBase™

3D PDX Screen

Quick Fact

3D PDX Screen

HuKemia®

Quick Fact

HuKemia®

HuPrime®

Quick Fact

HuPrime®

In Vitro and Ex Vivo Immuno-Oncology Drug Discovery

Application Note

In Vitro and Ex Vivo Immuno-Oncology Drug Discovery

OmniPanel™

Quick Fact

OmniPanel™

OncoExpress™

Quick Fact

OncoExpress™

OmniScreen™

Quick Fact

OmniScreen™

Radiation Therapy

Quick Fact

Radiation Therapy

Cell-Based Target Identification

Quick Fact

Cell-Based Target Identification

XenoSelect™ - Faster in vitro to in vivo study translation

Quick Fact

XenoSelect™ - Faster in vitro to in vivo study translation

XenoBase® - Which cell line is best for your cancer study?

Quick Fact

XenoBase® - Which cell line is best for your cancer study?

PrimePanel™

Quick Fact

PrimePanel™

Precision Profiling With PDX

White Paper

Precision Profiling With PDX

The Importance of Using an Isotype Control

White Paper

The Importance of Using an Isotype Control

Exploring Translational Capabilities of PDX Models across In Vivo, In Vitro, and Ex Vivo Applications

White Paper

Exploring Translational Capabilities of PDX Models across In Vivo, In Vitro, and Ex Vivo Applications

3 Strategies for Applying Humanized Models

White Paper

3 Strategies for Applying Humanized Models

How to Choose the Correct I/O Model

White Paper

How to Choose the Correct I/O Model

The Ultimate Guide to Mouse Clinical Trials

White Paper

The Ultimate Guide to Mouse Clinical Trials

Optimize Target Identification and MOA Studies

White Paper

Optimize Target Identification and MOA Studies