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Posters

Ex Vivo Functional Characterisation and In Vivo Efficacy Validation of Human CD40 Agonistic Antibodies in the Human CD40 Knock-In Model (CD40 HuGEMM™)

Date & Time: June 12th & 13th, 2019

Learn about the development and validation of a new CD40 knock-in model, expressing chimeric m/hCD40 for the evaluation of human-specific CD40 agonistic antibodies. Explore model response to human-specific anti-CD40 agonistic antibodies, and in vivo efficacy data for human CD40 agonists, alone and in combination with anti-PD-1 antibodies.

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