TIM-3 Antibody

Catalog # CA012

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Description

TIM-3 belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. TIM-3 is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance.

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Images


Western blot analysis of extracts of various cell lines, using TIM-3 antibody, catalog # CA012.

 

Product Details

Catalog #: CA012
Clone ID: Polyclonal
Host species: Rabbit
Ig subclass: IgG
Immunogen: Recombinant protein of human TIM-3
UniProt ID: Q8TDQ0
Gene ID: 84868
Synonyms: HAVCR2; KIM-3; TIMD3; Tim-3; TIMD-3; HAVcr-2
Calculated MW: 33 kDa
Observed MW: Refer to figure
Species Reactivity: Human, Mouse
Applications: WB
Recommended dilutions: WB: 1:500 - 1:2000
Purification Method: Affinity purified
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles.

100 ul - $255

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