PD-L2 Antibody (CB24)

Catalog # C0028

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Description

PD-L2 is involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.

This PD-L2 antibody was developed from mouse immunization, and expressed in suspension culture of mouse hybridoma clone CB24.

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Images


ELISA was performed using coated PD-L2 antigen (0.1ug per well) and PD-L2 antibody (CB24), Catalog # C0028.


FACS analysis of 5ug/mL PD-L2 antibody (CB24), Catalog # C0028, binding to PD-L2 cell line (3 x 105 cells per well, Catalog # C2025). Mouse IgG1, kappa isotype control (Catalog # C0005) was used as negative control.


Western blot analysis of PD-L2 ECD recombinant protein (0.1 ug per well) using 1ug/mL PD-L2 antibody (CB24), Catalog # C0028.

 

Product Details

Catalog #: C0028
Clone ID: CB24
Host species: Mouse
Ig subclass: IgG1
Immunogen: Human PD-L2, ECD domain
UniProt ID: Q9BQ51
Gene ID: 80380
Synonyms: PD-1 ligand 2, B7DC, CD273, PDCD1L2, PDL2
Species Reactivity: Human
Applications: ELISA, FACS, WB
Recommended dilutions: ELISA: 0.2-1.0 ug/mL
FACS: 1-5 ug/mL
WB: 1-10 ug/mL
QC: Endotoxin level: <2 EU/mg by the LAL method Purity: >95% by SDS-PAGE
Production Method: Expressed from mouse hybridoma clone CB24
Purification Method: Affinity purified
Buffer: PBS, pH 7.4
Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles.
Stable for 12 months from date of purchase when stored as recommended.

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