PD-1 Antibody

Catalog # CA010

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Description

PD-1 is a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases.

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Images


Western blot analysis of extracts of HEK-293 cell line, using PD-1 antibody, catalog # CA010.

 

Product Details

Catalog #: CA010
Clone ID: Polyclonal
Host species: Rabbit
Ig subclass: IgG
Immunogen: Recombinant protein of human PD-1
UniProt ID: Q15116
Gene ID: 5133
Synonyms: PDCD1; PD1; PD-1; CD279; SLEB2; hPD-1; hPD-l
Calculated MW: 32 kDa
Observed MW: Refer to figure
Species Reactivity: Human
Applications: WB, IHC, FC
Recommended dilutions: WB: 1:500 - 1:2000
IHC: 1:50 - 1:200
FC: 1:20 - 1:50
Purification Method: Affinity purified
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles.

100 ul - $275

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