OX40 Antibody

Catalog # CA009

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Description

OX40 is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation.

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Images


Western blot analysis of extracts of various cell lines, using OX40 antibody, catalog # CA009.

 

Product Details

Catalog #: CA009
Clone ID: Polyclonal
Host species: Rabbit
Ig subclass: IgG
Immunogen: Recombinant protein of human OX40
UniProt ID: P43489
Gene ID: 7293
Synonyms: TNFRSF4; OX40; ACT35; CD134; IMD16; TXGP1L;
Calculated MW: 29 kDa
Observed MW: Refer to figure
Species Reactivity: Human, Mouse, Rat
Applications: WB, IHC
Recommended dilutions: WB: 1:500 - 1:2000
IHC: 1:50 - 1:200
Purification Method: Affinity purified
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles.

100 ul - $255

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