IHC staining of formalin fixed and paraffin embedded human breast cancer tissue sections using NFκBp65 antibody (clone RM273) at a 1:1250 dilution.
NFkB is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological processes such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis (UniProt).
|Immunogen:||A peptide corresponding to the area near the C-terminus of human transcription factor p65 (NFkB p65 subunit).|
|Synonyms:||Transcription factor p65, RELA, NFKB3|
|Observed MW:||Refer to figure|
|Specificity:||This antibody reacts to human transcription factor p65 (NFkB p65 subunit).|
|Recommended dilutions:||IHC: 1:500 - 1:1500
WB: 1:500 - 1:1000
|Purification Method:||Protein A affinity purified from an animal origin–free culture supernatant|
|Buffer:||50% Glycerol/PBS with 1% BSA and 0.09% sodium azide|
|Storage Conditions:||Stable for 1 year at -20.0°C from date of receipt.|